| Cat. No. |
Product Name |
Information |
| PC-23917 |
JH-ENT-01
ENT1 inhibitor
|
JH-ENT-01 is a potent, specific inhibitor of the equilibrative nucleoside transporter subtype 1 (ENT1) with Ki of 92.7 nM, shows good selectivity for hENT1 over hENT2. |
| PC-23907 |
Norathyriol
CAS 3542-72-1
|
Norathyriol (Mangiferitin) is a natural metabolite of Mangifera, inhibits α-glucosidase in a noncompetitive manner with IC50 of 3.12 uM, also inhibits inhibits PPARα, PPARβ, and PPARγ with IC50 of 90-100 uM, is also an effective inhibitor that targets the MEG pocket on the circPETH-147aa surface. |
| PC-23847 |
ZiMo12.8
ZIP12 inhibitor
|
ZiMo12.8 is a small molecule inhibitor of astrocytic zinc transporter ZIP12. |
| PC-23825 |
BSc5367
Nek1 inhibitor
|
BSc5367 is a potent, selective inhibitor of NIMA-related protein kinase Nek1 (NimA related kinase 1) with IC50 of 11.5 nM. |
| PC-23822 |
Butylphthalide
6066-49-5
|
Butylphthalide (3-n-Butylphthalide, NBP) is an active molecule against cerebral ischemia, shows neuroprotective activity for acute ischemic stroke. |
| PC-23814 |
Cefcapene pivoxil hydrochloride hydrate
GSDMD inhibitor
|
Cefcapene pivoxil hydrochloride hydrate (Compound 98) is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity, also is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0. 32uM), exert pyroptosis inhibitory effects. |
| PC-23813 |
SCR-1481B1
GSDMD inhibitor
|
SCR-1481B1 (Metatinib anhydrous, Compound 68) is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0.4 uM), exert pyroptosis inhibitory effects, also shows inhibition on Met activation VEGFR. |
| PC-23808 |
ARC39
Acid sphingomyelinase inhibior
|
ARC39 is a direct, selective acid sphingomyelinase (ASM) inhibitor with IO50 of 20 nM, inhibits both lysosomal and secretory ASM in vitro. |
| PC-23800 |
LFHP-1c
PGAM5 inhibitor
|
LFHP-1c is a direct phosphoglycerate mutase family member 5 (PGAM5) inhibitor with binding SPR KD of 961 nM, not only inhibits the PGAM5 phosphatase activity, but also reduces the interaction of PGAM5 with NRF2. |
| PC-23794 |
KKT3054
KAI2 antagonist
|
KK181N1 is a specific inhibitor of karrikins (KARs) receptor KAI2, selectively inhibits Arabidopsis karrikin signaling, binds to the catalytic pocket of AtKAI2 with Kd of 14.9 uM. |
| PC-23793 |
KK181N1
KAI2 antagonist
|
KK181N1 is a specific inhibitor of karrikins (KARs) receptor KAI2, selectively depresses the KAR-induced phenotypes in Arabidopsis, binds to the catalytic pocket of AtKAI2 with Kd of 27.7 uM. |
| PC-23789 |
PQ529
QC/isoQC inhibitor
|
PQ529 is a selective glutaminyl cyclase (QC, QPCT) / isoenzyme of glutaminyl cyclase (isoQC, QPCTL) inhibitor. |
