| Cat. No. |
Product Name |
Information |
| PC-43315 |
D-Fagomine
Glycosidase inhibitor
|
D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively. |
| PC-43282 |
OAC2
Oct4 activator
|
Oct4-activating compound 2 (OAC2) is a small molecule Oct4-activating compound, enhances the iPSC reprogramming efficiency and accelerates the reprogramming process. |
| PC-43253 |
KHK-IN-8 hydrochloride
Ketohexokinase inhibitor
|
KHK-IN-8 hydrochloride is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM. |
| PC-43252 |
KHK-IN-8
Ketohexokinase inhibitor
|
KHK-IN-8 is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM. |
| PC-43251 |
OBA-09
|
OBA-09 is a simple ester of pyruvate and salicylic acid, main metabolites of pyruvate and aspirin, respectively, exerts robust neuroprotective effect in the postischemic brain in vivo. |
| PC-43248 |
EN460
ERO1 inhibitor
|
EN460 is a specific mall molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1), interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation (IC50=1.9 uM). |
| PC-43242 |
AMZ30
PME-1 inhibitor
|
AMZ30 is a potent, selective, covalent inhibitor of the serine hydrolase protein phosphatase methylesterase-1 (PME-1) with IC50 of 0.6 uM, >100-fold selectivity over other SHs. |
| PC-43236 |
Sortin1
Sorting inhibitor
|
Sortin1 is a small molecule sorting inhibitor (Sortin) that induces reversible defects in vacuole biogenesis and root development in Arabidopsis seedlings at 100 mg/liter (227 uM). |
| PC-43231 |
AEBSF
Serine protease inhibitor
|
AEBSF is an irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. |
| PC-43219 |
AF38469
Sortilin inhibitor
|
AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM. |
| PC-43218 |
DiZPK
Photocrosslinking agent
|
DiZPK is a genetically encoded, highly efficient photocrosslinking amino acid valuable in unveiling the physiological interaction partners of given proteins and their functions. |
| PC-43171 |
Genz-123346
Glucosylceramide synthase inhibitor
|
Genz-123346 is a potent, specific glucosylceramide synthase (GCS) inhibitor with IC50 of 14 nM (GM1 inhibition), does not inhibit α-glucosidase or glucocerebrosidase and little effect on 1-O-acylceramide synthase activity. |
