| Cat. No. |
Product Name |
Information |
| PC-43218 |
DiZPK
Photocrosslinking agent
|
DiZPK is a genetically encoded, highly efficient photocrosslinking amino acid valuable in unveiling the physiological interaction partners of given proteins and their functions. |
| PC-43171 |
Genz-123346
Glucosylceramide synthase inhibitor
|
Genz-123346 is a potent, specific glucosylceramide synthase (GCS) inhibitor with IC50 of 14 nM (GM1 inhibition), does not inhibit α-glucosidase or glucocerebrosidase and little effect on 1-O-acylceramide synthase activity. |
| PC-43170 |
Genz-123346 free base
Glucosylceramide synthase inhibitor
|
Genz-123346 is a potent, specific glucosylceramide synthase inhibitor with IC50 of 14 nM (GM1 inhibition), does not inhibit α-glucosidase or glucocerebrosidase and little effect on 1-O-acylceramide synthase activity. |
| PC-43150 |
Succinyl phosphonate
KGDHC inhibitor
|
Succinyl phosphonate is an α-Ketoglutarate phosphoanalogue, α-ketoglutarate dehydrogenase inhibitor, effectively inhibits α-ketoglutarate oxidative decarboxylation. |
| PC-63231 |
TJ191
|
TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM). |
| PC-63220 |
VUT-MK142
Cardiomyogenic agent
|
VUT-MK142 is a cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, shows superior cardiomyogenic activity over cardiogenol C. |
| PC-63195 |
RCGD 423
gp130 modulator
|
RCGD 423 (RCGD423) is a small molecule gp130 modulator that prevents articular cartilage degeneration and promotes repair both in vitro and in vivo. |
| PC-43111 |
Thiamet G
O-GlcNAcase inhibitor
|
Thiamet-G is a potent, selective O-GlcNAcase inhibitor with Ki of 21 nM for human O-GlcNAcase, blocks phosphorylation of tau both in vitro and in vivo. |
| PC-43102 |
Sermorelin
GHRH analog
|
Sermorelin (GHRH (1-29)) is a peptide analogue of growth hormone-releasing hormone (GHRH) which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. |
| PC-42996 |
FH1
|
FH1 (BRDK4477) is a small molecule that increase function and proliferation of primary human hepatocytes, promotes the differentiation of iPS-derived hepatocytes. |
| PC-42932 |
XEN445
Endothelial lipase inhibitor
|
XEN445 is a potent, selective endothelial lipase (EL) inhibitor with IC50 of 237 nM, displays no significant activity against lipoprotein lipase (LPL) and hepatic lipase (HL) (IC50=20 and 9.5 uM). |
| PC-42915 |
PFK15
PFKFB3 inhibitor
|
PFK15 (PFK 015) is a potent, selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor with IC50 of 207 nM against recombinant human PFKFB3, displays 100-fold more activity than 3PO. |
