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BIO124

Chemical Structure : BIO124

CAS No.:

BIO124 (BIO-124, BIO 124)

Catalog No.: PC-35430Not For Human Use, Lab Use Only.

BIO124 (BIO-124) is a modest inhibitor of the PICK1-GluA2 interaction with IC50 of 0.51 uM in FP assays, binds to the PDZ domain of PICK1.

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    Biological Activity

    BIO124 (BIO-124) is a modest inhibitor of the PICK1-GluA2 interaction with IC50 of 0.51 uM in FP assays, binds to the PDZ domain of PICK1.

    Physicochemical Properties

    M.Wt 606.558
    Formula C29H40BrN3O6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-(4-(4-bromophenyl)-1-((tert-butoxycarbonyl)-L-prolyl)piperidine-4-carboxamido)-2-cyclopentylacetic acid

    References

    1. Marcotte DJ, et al. Protein Sci. 2018 Mar;27(3):672-680.

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