Catalog No.: PC-35371Not For Human Use, Lab Use Only.
Edonerpic maleate (T-817MA) is a neurotrophic agent that can protects neuronal cells and modifies their morphology, binds to collapsin-response-mediator-protein 2 (CRMP2) and inhibits amyloid-β peptides (Aβ).
Edonerpic maleate (T-817MA) is a neurotrophic agent that can protects neuronal cells and modifies their morphology, binds to collapsin-response-mediator-protein 2 (CRMP2) and inhibits amyloid-β peptides (Aβ).
Edonerpic maleate binds to collapsin-response-mediator-protein 2 (CRMP2) with Kd of 7.35 x 10−4 M.
Edonerpic maleate attenuates amyloid-beta-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons.
Edonerpic maleate ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide.
