Chemical Structure : Edonerpic maleate
Catalog No.: PC-35371Not For Human Use, Lab Use Only.
Edonerpic maleate (T-817MA) is a neurotrophic agent that can protects neuronal cells and modifies their morphology.
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Edonerpic maleate (T-817MA) is a neurotrophic agent that can protects neuronal cells and modifies their morphology; binds to collapsin-response-mediator-protein 2 (CRMP2) with Kd of 7.35 x 10−4 M; attenuates amyloid-beta-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons; ameliorates the deficits in adult neurogenesis and spatial memory in rats infused i.c.v. with amyloid-beta peptide.
M.Wt | 407.481 | |
Formula | C20H25NO6S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Abe H, et al. Science. 2018 Apr 6;360(6384):50-57.
2. Hirata K, et al. J Pharmacol Exp Ther. 2005 Jul;314(1):252-9.
3. Fukushima T, et al. Biochem Biophys Res Commun. 2011 Apr 22;407(4):730-4.
4. Kimura T, et al. Br J Pharmacol. 2009 Jun;157(3):451-63.
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