Catalog No.: PC-35366Not For Human Use, Lab Use Only.
Lipofermata (CB16.2 aka) is a specific fatty acid transport (FATP) inhibitor, blocks human FATP2-mediated fatty acid uptake (IC50=4.84 uM in Caco-2 cells) without impacting other cellular functions.
Lipofermata (CB16.2 aka) is a specific fatty acid transport (FATP) inhibitor, blocks human FATP2-mediated fatty acid uptake (IC50=4.84 uM in Caco-2 cells) without impacting other cellular functions.
Lipofermata demonstrates cellualr transport inhibition activity models for myocytes (mmC2C12), pancreatic β-cells (rnINS-1E), intestinal epithelial cells (hsCaco-2), and hepatocytes (hsHepG2), as well as primary human adipocytes, which is specific for long and very long chain fatty acids but has no effect on medium chain fatty acids (C6-C10).
Lipofermata also abrogates lipid transport into melanoma cells and reduces melanoma growth and invasion.
