| Cat. No. |
Product Name |
Information |
| PC-72066 |
SAR439883
PKR inhibitor
|
SAR439883 (SAR 439883) is a novel potent, selective, orally active PKR inhibitor with IC50 of 0.68/0.69 uM against hPKR/mPKR, respectively. |
| PC-72048 |
YE6144
IRF5 inhibitor
|
YE6144 (YE 6144) is a specific small molecule inhibitor of transcription factor IFN regulatory factor 5 (IRF5), selectively suppresses IRF5 activity through inhibition of IRF5 phosphorylation. |
| PC-72047 |
IRF5 inhibitor N5-1
IRF5 inhibitor
|
IRF5 inhibitor N5-1 (PRRVRLK) is a cell permeable, IRF5 peptide mimetic that selectively bind to and stabilizes the inactive IRF5 monomer with KD of 98.8 nM. |
| PC-72031 |
ARH3 inhibitor 26
ARH3 inhibitor
|
ARH3 inhibitor 26 (AI26) is a small molecule ADP-ribosylhydrolase ARH3 inhibitor that binds to the catalytic pocket of ARH3 and inhibits the enzymatic activity of ARH3 with IC50 of 2.41 uM in vitro. |
| PC-72028 |
NIO-1
OCT1 inhibitor
|
NIO-1 (Novel inhibitor of OCT1) is a novel small molecule inhibitor of Octamer transcription factor OCT1, inhibits OCT1 activation with IC50 of 0.11 uM. |
| PC-72024 |
SU0268
OGG1 inhibitor
|
SU0268 (SU 0268) is a potent, selective, noncovalent inhibitor DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) with IC50 of 59 nM. |
| PC-72022 |
BIM5078
HNF4α antagonist
|
BIM5078 (BIM-5078) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity (EC50=11.9 nM) and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
| PC-72021 |
BI6015
HNF4α antagonist
|
BI6015 (BI-6015) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
| PC-72020 |
ART558
Polθ inhibitor
|
ART558 (ART-558) is a highly potent, selective, allosteric inhibitor of the polymerase function of DNA polymerase Polθ with IC50 of 7.9 nM. |
| PC-72017 |
INI-60
Kpnβ1 inhibitor
|
INI-60 (Inhibitor of Nuclear Import-60) is a novel small molecule inhibitor of Kpnβ1-mediated nuclear import with anti-cancer activity. |
| PC-72015 |
INI-43
Kpnβ1 inhibitor
|
INI-43 (Inhibitor of Nuclear Import-43, ZINC20547783) is a small molecule that bind nuclear import receptor Karyopherin beta 1 (Kpnβ1), inhibits Kpnβ1-mediated nuclear import with anti-cancer activity. |
| PC-72005 |
Reproxalap
RASP inhibitor
|
Reproxalap (ADX-102) is a novel inhibitor of reactive aldehyde species (RASP) for the treatment of ocular inflammation. |
