| Cat. No. |
Product Name |
Information |
| PC-72215 |
BJP-06-005-3
Pin1 inhibitor
|
BJP-06-005-3 is a potent, selective, covalent, cell-permeable peptide Pin1 inhibitor (Ki=48 nM) that covalently target Cys113, a highly conserved cysteine located in the Pin1 active site. |
| PC-72175 |
OXS007417
AML differentiation inducer
|
OXS007417 (OXS 007417) is a small moelcule that induces differentiation of AML cells in vitro (CD11b increasein HL-60 cell EC50=48 nM) and shows antitumor effects in vivo. |
| PC-72156 |
I194496
CSE inhibitor
|
I194496 (I 194496) is a novel potent, selective inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 0.79 uM. |
| PC-72155 |
L-Propargylglycine
CSE inhibitor
|
L-Propargylglycine (L-PAG) is the most commonly used, covalently irreversible inhibitor inhibitor of cystathionine γ-lyase (CSE). |
| PC-72154 |
CSE inhibitor 43
CSE inhibitor
|
CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM. |
| PC-72143 |
PCLX-001
N-myristoyl-transferase inhibitor
|
PCLX-001 (Zelenirstat) is a potent, selective, orally bioavailable N-myristoyl-transferases (NMT1/2) inhibitor with IC50 of 5/8 nM, respectively. |
| PC-72138 |
NSC 773097
|
NSC 773097 is a RITA analog that produces hyperselective cytotoxicity while maintaining antitumor efficacy (A498 cell IC50=130 nM). |
| PC-72132 |
BD50265
GPR52 agonist
|
BD50265 (BD 50265) is a potent small-molecule GPR52 agonist. |
| PC-72130 |
WO-459
GPR52 agonist
|
WO-459 (WO459) is the first potent and orally available agonist of GPR52 with pEC50 of 7.53. |
| PC-72129 |
GPR52 antagonist E7
GPR52 antagonist
|
GPR52 antagonist E7 is a novel Gpr52 antagonist, shows significant inhibitory effect on WO-459 (100 nM)-induced cAMP elevation in HEK293/GPR52 cells with IC50 of 12.0 uM. |
| PC-72128 |
CAY10786
GPR52 antagonist
|
CAY10786 (GPR52 antagonist Comp-43) is a highly potent and specific GPR52 antagonist with IC50 of 0.63 uM. |
| PC-72127 |
PW0787
GPR52 agonist
|
PW0787 (PW 0787) is a potent, selective, brain-penetrant GPR52 agonist with EC50 of 135 nM in cAMP assays in HEK293 cells. |
