Cat. No. |
Product Name |
Information |
PC-72103 |
AM9053
NAAA inhibitor
|
AM9053 (AM 9053) is a potent, selective inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 30 nM, with limited effect on FAAH activity (IC50>100 uM). |
PC-72102 |
ARN19689
NAAA inhibitor
|
ARN19702 (ARN-19702) is potent, selective, non-covalent inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 42 nM (h-NAAA). |
PC-72101 |
ARN19702
NAAA inhibitor
|
ARN19702 (ARN-19702) is potent, selective, orally active, reversible inhibitor of N-Acylethanolamine acid amidase (NAAA) with IC50 of 230 nM. |
PC-72080 |
GMFBI.1
GMF-β inhibitor
|
GMFBI.1 is a small molecule that specifically block Ser83 phosphorylation site on Glia maturation factor-β (GMF-β), directly binds to hGMF-β protein with Kd of 19.9 uM. |
PC-72079 |
INH-12
HSD17B12 inhibitor
|
INH-12 is a selective small-molecule HSD17B12 inhibitor with 70% inhibition of HSD17B12 activity to transform estrone (E1) into estradiol (E2) at 1 uM, reduces the replication of Flaviviridae viruses (HCV, DENV and ZIKV). |
PC-72078 |
NCGC00507974
Mir155 inhibitor
|
NCGC00507974 is a small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 1.2 uM. |
PC-72077 |
NCGC00108248
Mir155 inhibitor
|
NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM. |
PC-72076 |
ClpXP inhibitor 334
ClpXP inhibitor
|
ClpXP inhibitor 334 is a small molecule inhibitor of the mitochondrial ClpXP protease with anti-cancer activity. |
PC-72071 |
hNPR1 inhibitor JS-11
NPR1 inhibitor
|
hNPR1 inhibitor JS-11 is a selective small-molecule inhibitor of NPPB receptor NPR1 (natriuretic peptide receptor 1), does not inhibit adenylate cyclases (ACs) family of enzymes. |
PC-72067 |
ALC-0159
PEGylated lipid
|
ALC-0159 is a PEGylated lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0159 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0315, DSPC, and cholesterol. |
PC-72066 |
SAR439883
PKR inhibitor
|
SAR439883 (SAR 439883) is a novel potent, selective, orally active PKR inhibitor with IC50 of 0.68/0.69 uM against hPKR/mPKR, respectively. |
PC-72048 |
YE6144
IRF5 inhibitor
|
YE6144 (YE 6144) is a specific small molecule inhibitor of transcription factor IFN regulatory factor 5 (IRF5), selectively suppresses IRF5 activity through inhibition of IRF5 phosphorylation. |