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BAY-179

Chemical Structure : BAY-179

CAS No.: 2764880-87-5

BAY-179 (BAY179)

Catalog No.: PC-72520Not For Human Use, Lab Use Only.

BAY-179 (BAY179) is a potent, selective, and species cross-reactive Complex I inhibitor with IC50 of 79 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BAY-179 (BAY179) is a potent, selective, and species cross-reactive Complex I inhibitor with IC50 of 79 nM.
BAY-179 is an excellent in vivo suitable tool with which to probe the biological relevance of complex I inhibition in cancer indications.

Physicochemical Properties

M.Wt 415.515
Formula C23H21N5OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-((1H-imidazo[4,5-b]pyridin-2-yl)methyl)piperidin-4-yl)-4-(benzofuran-2-yl)thiazole

References

1. Mowat J, et al. ACS Med Chem Lett. 2022 Feb 18;13(3):348-357.

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