| Cat. No. |
Product Name |
Information |
| PC-23814 |
Cefcapene pivoxil hydrochloride hydrate
GSDMD inhibitor
|
Cefcapene pivoxil hydrochloride hydrate (Compound 98) is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity, also is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0. 32uM), exert pyroptosis inhibitory effects. |
| PC-23813 |
SCR-1481B1
GSDMD inhibitor
|
SCR-1481B1 (Metatinib anhydrous, Compound 68) is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0.4 uM), exert pyroptosis inhibitory effects, also shows inhibition on Met activation VEGFR. |
| PC-23800 |
LFHP-1c
PGAM5 inhibitor
|
LFHP-1c is a direct phosphoglycerate mutase family member 5 (PGAM5) inhibitor with binding SPR KD of 961 nM, not only inhibits the PGAM5 phosphatase activity, but also reduces the interaction of PGAM5 with NRF2. |
| PC-23794 |
KKT3054
KAI2 antagonist
|
KK181N1 is a specific inhibitor of karrikins (KARs) receptor KAI2, selectively inhibits Arabidopsis karrikin signaling, binds to the catalytic pocket of AtKAI2 with Kd of 14.9 uM. |
| PC-23793 |
KK181N1
KAI2 antagonist
|
KK181N1 is a specific inhibitor of karrikins (KARs) receptor KAI2, selectively depresses the KAR-induced phenotypes in Arabidopsis, binds to the catalytic pocket of AtKAI2 with Kd of 27.7 uM. |
| PC-23789 |
PQ529
QC/isoQC inhibitor
|
PQ529 is a selective glutaminyl cyclase (QC, QPCT) / isoenzyme of glutaminyl cyclase (isoQC, QPCTL) inhibitor. |
| PC-23787 |
PFKFB2 inhibitor B2
PFKFB2 inhibitor
|
PFKFB2 inhibitor B2 is a small molecule inhibitor of PFKFB2 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2) with IC50 of 3.29 uM, inhibits PFKFB3 with IC50 of 11.89 uM. |
| PC-23758 |
MTDH-SND1 PPI inhibitor C19
MTDH-SND1 inhibitor
|
MTDH-SND1 PPI inhibitor C19 is a small-molecule inhibitor of MTDH-SND1 PPI with IC50 of 487 nM, directly binds to the SND1-purified protein, degrades SND1 and downregulates downstream at the protein level. |
| PC-23750 |
Dauricine
STK11 agonist
|
Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum, has anti-inflammatory activity, Dauricine is a natural agonist of STK11 (Serine/threonine kinase 11). |
| PC-23732 |
Ln268
PGK1 inhibitor
|
Ln268 is a potent Lin28 inhibitor, inhibits Lin28:pre-let-7d complex formation in a dose-dependent manner, inhibits Lin28b at both mRNA and protein level, specifically inhibits various Lin28-positive cancer cells. |
| PC-23731 |
Z57346765
PGK1 inhibitor
|
Z57346765 is a phosphoglycerate kinase 1 (PGK1) inhibitor, significantly reduces the metabolic enzyme activity of PGK1 in glycolysis, inhibits KIRC cell proliferation. |
| PC-23722 |
QP5020
QPCTL inhibitor
|
QP5020 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 15 nM. |
