| Cat. No. |
Product Name |
Information |
| PC-28360 |
XJB-5-131
Antioxidant
|
XJB-5-131 is hemigramicidin-TEMPO conjugate and mitochondria-targeted ROS and electron scavenger, reduces apoptosis and enhances cell survival in mouse embryonic cells in vitro, improves mitochondrial function. |
| PC-28349 |
Herbacetin
Ornithine decarboxylase inhibitor
|
Herbacetin is a naturally occurring flavonoid and potent, specific, allosteric ornithine decarboxylase (ODC) inhibitor, exhibits potent anticancer activity in colon cancer cell lines expressing high levels of ODC. |
| PC-28332 |
PANK-IN-3
PANK3 inhibitor
|
PANK-IN-3 is a high-affinity, selective inhibitor of PANK3 (Pantothenate kinase 3) with Ki of 4.2 nM, 104-fold selective over PanK1β. |
| PC-28331 |
PANK-IN-2
PANK inhibitor
|
PANK-IN-2 is a poten tinhibitor of Pantothenate kinase (PANK) with IC50 of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3 respectively in radiochemical enzyme assays. |
| PC-28330 |
PANK-IN-1
PANK3 inhibitor
|
PANK-IN-1 is a potent, pantothenate competitive inhibitor of Pantothenate kinase (PANK) with IC50 of 0.51 uM against PANK3. |
| PC-28291 |
Racemetirosine
Tyrosine hydroxylase inhibitor
|
Racemetirosine (Alpha-methyltyrosine, alphaMT, Alpha-methyl-para-tyrosine) is a competitive small molecule tyrosine hydroxylase inhibitor, inhibits catecholamine biosynthesis, blocks hydroxylation of tyrosine into dihydroxyphenylalanine (DOPA). |
| PC-28249 |
SARM1 inhibitor B339
SARM1 inhibitor
|
SARM1 inhibitor B339 is a potent SARM1 inhibitor with IC50 of 7.215 uM, shows potential in prevention of axonal degeneration. |
| PC-28230 |
NSC 65828 sodium
Angiogenin inhibitor
|
NSC 65828 sodium (NCI-65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM; possess antitumor activity in mice. |
| PC-28145 |
FM029
FOXP3-T-bet stabliezer
|
FM029 is a direct FOXP3 targeting small molecule that binds to FOXP3 (SPR KD=1.13 uM), stabilizes the FOXP3-T-bet interaction to represses T-bet-driven IFN-γ production. |
| PC-28105 |
SEP-227900
DAAO inhibitor
|
SEP-227900 is an orally active small molecule D-amino-acid oxidase (DAAO) inhibitor. |
| PC-28104 |
AS057278
DAAO inhibitor
|
AS057278 (MPCA, U-19425) is a potent, selective, orally active and blood-brain barrier (BBB) penetrant D-amino acid oxidase (DAAO) inhibitor with IC50 of 0.91 uM, shows potential anti-psychotic properties, also inhibits adipocyte lipolysis. |
| PC-28054 |
MOG (35-55) mouse, rat
MOG peptide
|
MOG (35-55) mouse, rat is a myelin oligodendrocyte glycoprotein (MOG) peptide derived from the extracellular domain of MOG protein and key immunodominant epitope extensively utilized in the study of autoimmune demyelinating diseases of the central nervous system (CNS), induce experimental autoimmune encephalomyelitis (EAE) in susceptible animal models, particularly C57BL/6 mice. |
