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Chemical Structure : RTI-263
Catalog No.: PC-21471Not For Human Use, Lab Use Only.
RTI-263 (SerPheLysAsn-NH2) is a potent, selective tetrapeptide neuropeptide S receptor (NPSR, GPR154) biased agonist with EC50 of 3.02 nM for hNPSR calcium mobilization.
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RTI-263 (SerPheLysAsn-NH2) is a potent, selective tetrapeptide neuropeptide S receptor (NPSR, GPR154) biased agonist with EC50 of 3.02 nM for hNPSR calcium mobilization.
RTI-263 greatly attenuated hyperlocomotor stimulation in vivo but retains activity in assays that correlate with memory consolidation and anxiolytic activity.
RTI-263 has a bias for the calcium mobilization pathway, at the human and mouse NPSR receptor.
| M.Wt | 493.57 | |
| Formula | C22H35N7O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Stewart D Clark, et al. Neuropharmacology. 2017 May 15:118:69-78.
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