AEP inhibitor 18

Chemical Structure : AEP inhibitor 18

Catalog No.: PC-21548Not For Human Use, Lab Use Only.

AEP inhibitor 18 is a potent, selective, orally bioavailable, and brain penetrant inhibitor of asparagine endopeptidase (AEP) with IC50 of 7.8 nM.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

Get Quotation Now

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

AEP inhibitor 18 is a potent, selective, orally bioavailable, and brain penetrant inhibitor of asparagine endopeptidase (AEP) with IC50 of 7.8 nM.

M.Wt	455.41
Formula	C21H21F4N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,4R)-4-Fluoro-N-[(1S)-1-(2-amino-2-oxo-ethyl)prop-2-ynyl]-1-[1-[4-(trifluoromethoxy)phenyl]cyclopropanecarbonyl]pyrrolidine-2-carboxamide

1. Krummenacher D, et al. J Med Chem. 2023 Dec 13. doi: 10.1021/acs.jmedchem.3c01804.