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AGI-43192

Chemical Structure : AGI-43192

CAS No.: 2377491-54-6

AGI-43192 (AGI 43192 )

Catalog No.: PC-21475Not For Human Use, Lab Use Only.

AGI-43192 is a potent and selective methionine adenosyltransferase 2A (MAT2A) inhibitor with cellular IC50 of 14 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AGI-43192 is a potent and selective methionine adenosyltransferase 2A (MAT2A) inhibitor with cellular IC50 of 14 nM.

Physicochemical Properties

M.Wt 484.87
Formula C23H16ClF3N6O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-chlorophenyl)-6-(2-methyl-2H-indazol-5-yl)-2-[(2,2,2-trifluoroethyl)amino]-

References

1. Mingzong Li, et al. J Med Chem. 2022 Mar 24;65(6):4600-4615.

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