Chemical Structure : AGI-43192
CAS No.: 2377491-54-6
Catalog No.: PC-21475Not For Human Use, Lab Use Only.
AGI-43192 is a potent and selective methionine adenosyltransferase 2A (MAT2A) inhibitor with cellular IC50 of 14 nM.
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AGI-43192 is a potent and selective methionine adenosyltransferase 2A (MAT2A) inhibitor with cellular IC50 of 14 nM.
M.Wt | 484.87 | |
Formula | C23H16ClF3N6O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-chlorophenyl)-6-(2-methyl-2H-indazol-5-yl)-2-[(2,2,2-trifluoroethyl)amino]- |
1. Mingzong Li, et al. J Med Chem. 2022 Mar 24;65(6):4600-4615.
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