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Brefeldin A

Chemical Structure : Brefeldin A

CAS No.: 20350-15-6

Brefeldin A

Catalog No.: PC-21460Not For Human Use, Lab Use Only.

Brefeldin A is a lactone antibiotic and a specific inhibitor of protein trafficking, blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.

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Biological Activity

Brefeldin A is a lactone antibiotic and a specific inhibitor of protein trafficking, blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.
Brefeldin A is also an autophagy and mitophagy inhibitor and CRISPR/Cas9 activator.
Brefeldin A inhibits HSV-1 and has anti-cancer activity.

Physicochemical Properties

M.Wt 280.36
Formula C16H24O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one

References

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