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Cat. No. Product Name Information
PC-38248

PF-06835919

Ketohexokinase inhibitor

PF-06835919 (PF 06835919) is a first-in-class, potent, selective Ketohexokinase (KHK) inhibitor with IC50 of 10 nM (hKHK).
PC-38247

GSK716

Zα1-antitrypsin inhibitor

GSK716 (GSK-716) is a potent inhibitor of Z α1-antitrypsin polymerisation, binds to Zα1-antitrypsin with a high-affinity (pKD=8.5).
PC-38246

BAM15

Mitochondrial uncoupler

BAM15 (Mitochondrial uncoupler BAM15) is a potent protonophore that uncouples the mitochondria without depolarizing the plasma membrane, oxidative phosphorylation (OXPHOS) uncoupler.
PC-38243

mitoNEET Ligand-1

mitoNEET ligand

mitoNEET Ligand-1 (NL-1) is a small molecule ligand of mitoNEET, a protein that regulate the oxidative capacity of the mitochondria.
PC-38227

DCLK1-IN-1

DCLK1 inhibitor

DCLK1-IN-1 is the first potent, selective inhibitor of the DCLK1 and DCLK2 kinases with IC50 of 9.5 nM and 31 nM in binding assays, respectively.
PC-38225

TH7285

TH7285 is the negative control compound (IC50>100 uM) of TH1760, a potent, selective NUDT15 inhibitor.
PC-38224

Cas9 inhibitor 85

Cas9 inhibitor

Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.
PC-38216

UNC10245092

CIB1 inhibitor

UNC10245092 is a high affinity peptide inhibitor of Calcium and integrin binding protein 1 (CIB1), binds hydrophobic pocket on CIB1 with Kd of 29.4 nM..
PC-38215

UNC10245350

CIB1 inhibitor

UNC10245351 is a N-terminal HIV Tat conjugate to UNC10245092, a CIB1 peptide inhibitor (Kd=192 nM), cell-penetrating.
PC-38214

H3B-120

CPS1 inhibitor

H3B-120 (H3B 120) is a selective allosteric inhibitor of Carbamoyl phosphate synthetase 1 (CPS1) with Ki of 1.4 uM, does not bind to CPS2.
PC-38213

H3B-616

CPS1 inhibitor

H3B-616 (H3B 616) is a potent, selective allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 66 nM, demonstrates no appreciable inhibition of CPS2 (IC50>100 uM).
PC-38212

KLK6 inhibitor 32

KLK6 inhibitor

KLK6 inhibitor 32 is a potent and selective inhibitor of kallikrein‐related peptidase 6 (KLK6) with IC50 of 2.5 nM, high selectivity against KLK7, KLK8, Trypsin, Thrombin.

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