NCGC00108248 | Mir155 inhibitor | Probechem Biochemicals

Chemical Structure : NCGC00108248

NCGC00108248 (NCGC 00108248)

Catalog No.: PC-72077Not For Human Use, Lab Use Only.

NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM.

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Biological Activity

NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM.
NCGC00108248 inhibited IL-17 production in the Th17 differentiation assay in CD4+ T cells (IC90=20 uM).

Physicochemical Properties

M.Wt	485.414
Formula	C22H17BrN2O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-1-((4-bromophenyl)sulfonyl)-2-(4-(methylthio)styryl)-1H-benzo[d]imidazole

References

1. Anju Singh, et al. Sci Rep. 2021 Jun 1;11(1):11498.

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NCGC00108248 (NCGC 00108248)

Biological Activity

Physicochemical Properties

References

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