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NCGC00108248

Chemical Structure : NCGC00108248

CAS No.: 901014-45-7

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NCGC00108248 (NCGC 00108248)

Catalog No.: PC-72077Not For Human Use, Lab Use Only.

NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NCGC00108248 is small molecule inhibitor of Mir155 reporter, dose-dependently inhibits Mir155 reporter expression with EC50 of 2.2 uM.
    NCGC00108248 inhibited IL-17 production in the Th17 differentiation assay in CD4+ T cells (IC90=20 uM).

    Physicochemical Properties

    M.Wt 485.414
    Formula C22H17BrN2O2S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-1-((4-bromophenyl)sulfonyl)-2-(4-(methylthio)styryl)-1H-benzo[d]imidazole

    References

    1. Anju Singh, et al. Sci Rep. 2021 Jun 1;11(1):11498.

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