| Cat. No. |
Product Name |
Information |
| PC-27125 |
CTL4 inhibitor DT-13
CTL4 inhibitor
|
CTL4 inhibitor DT-13 is a potent small molecule choline transporter-like protein 4 (CTL4) inhibitor with IC50 of 12.47 uM, directly binds to CTL4 with MST Kd of 0.64 uM, inhibits CTL4-mediated choline uptake. |
| PC-27098 |
Creatine transporter 1-IN-1
CT1/SLC6A8 inhibitor
|
Creatine transporter 1-IN-1 is a small molecule creatine transporter 1 (CT1, SLC6A8), inhibits substrate uptake by CT1 in CT1 expressing HEK293 cells with IC50 of 55 uM. |
| PC-27082 |
OICR-403184
PKR inhibitor
|
OICR-403184 is a potent, selective inhibitor of RNA-dependent protein kinase PKR with IC50 of 263 nM, shows minimal activity against related eIF2α kinases and BRAF. |
| PC-27060 |
CIB-Q22
Pyruvate carboxylase inhibitor
|
CIB-Q22 is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 1.74 nM, suppresses HCC cell viability (IC50=25.18 nM). |
| PC-27059 |
Pyruvate Carboxylase-IN-1
Pyruvate carboxylase inhibitor
|
Pyruvate Carboxylase-IN-1 (Compound 37) is a potent pyruvate carboxylase (PC) inhibitor with IC50 of 204 nM and 104 nM for PC in cell lysates and cells, shows antiproliferative activity against human hepatocellular carcinoma (HCC). |
| PC-27058 |
Pyruvate Carboxylase-IN-5
Pyruvate carboxylase inhibitor
|
Pyruvate Carboxylase-IN-5 (Compound 6m) is a selective pyruvate carboxylase (PC) inhibitor with IC50 of 3.4 uM. |
| PC-27057 |
U73343
CH25H inhibitor
|
U-73343 (U73343) an inactive analog of phospholipase C (PLC) inhibitor U73122, also is a potent enhancer of oligodendrocyte formation that induces 8,9-unsaturated sterol accumulation by inhibition of cholesterol biosynthesis enzyme sterol 14-reductase, also inhibits cholesterol 25-hydroxylase (CH25H). |
| PC-27050 |
Commendamide
GPR132 agonist
|
Commendamide is natively produced by commensal Bacteroides and specific agonist of GPCR G2A/GPR132 with EC50 of 11.8 uM, attenuates skeletal muscle ferroptosis in vitro. |
| PC-27048 |
SB-583831
GPR132 agonist
|
SB-583831 is a potent, selective agonist of G‐protein‐coupled receptor GPR132 (G2A) with pEC50 of 7.7 and 7.3 in yeast and β‐arrestin assays (human GPR132a). |
| PC-26995 |
SIPI11594
MPC inhibitor
|
SIPI11594 is a small molecule mitochondrial pyruvate carrier (MPC) inhibitor, shows cellular lactate production-enhancing activity, significantly accelerates hair regrowth and anagen entry. |
| PC-26982 |
Zearalenone
Endocrine disruptor
|
Zearalenone (Mycotoxin F2, Toxin F2) is a potent endocrine disruptor that poses serious health risks through reproductive toxicity. |
| PC-26955 |
UCM-1336
ICMT inhibitor
|
UCM-1336 is a potent, selective isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor with IC50 of 2 uM. |
