| Cat. No. |
Product Name |
Information |
| PC-21327 |
ENPP1 inhibitor 29f hydrochloride
ENPP1 inhibitor
|
ENPP1 inhibitor 29f hydrochloride is a potent, orally active inhibitor of ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), inhibits the cGAMP hydrolysis by ENPP1 in vitro with IC50 of 68 nM. |
| PC-21326 |
ENPP1 inhibitor 29f
ENPP1 inhibitor
|
ENPP1 inhibitor 29f is a potent, orally active inhibitor of ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1), inhibits the cGAMP hydrolysis by ENPP1 in vitro with IC50 of 68 nM. |
| PC-21325 |
MV-658
ENPP1 inhibitor
|
MV658 a potent small molecule ENPP1 inhibitor (IC50=11 nM) as immune modulator. |
| PC-21318 |
PSB-22034
MRGPRX4 agonist
|
PSB-22034 is a potent, selective agonist of MAS-related Gq protein-coupled receptor X4 (MRGPRX4) with EC50 of 11.2 nM/32.0 nM in Ca2+ assay/β-arrestin assays (variant 83S), respectively. |
| PC-21313 |
HsClpP activator ZK53
HsClpP activator
|
HsClpP activator ZK53 is a potent, selective activator of mitochondrial caseinolytic protease P (HsClpP) with EC50 of 0.22 uM in FI-based protease activity assays, inactive toward bacterial ClpP proteins. |
| PC-21295 |
PTC-124
Readthrough promoter
|
PTC-124 (Ataluren, PTC124) is an orally bioavailable small molecule that selectively induces ribosomal readthrough of premature but not normal termination codons. |
| PC-21293 |
KRP-6
MIF inhibitor
|
KRP-6 is a potent and highly selective macrophage migration inhibitory factor (MIF) ketonase inhibitor with IC50 of 4.31 uM, significantly reduces MIF-induced neutrophil migration. |
| PC-21275 |
ARUK2002821
PI5P4Kα inhibitor
|
ARUK2002821 is a potent, selective PI5P4Kα inhibitor with pIC50 of 8.0, >1000-fold selective over PI5P4Kγ. |
| PC-21274 |
ARUK2007145
PI5P4Kα/γ inhibitor
|
ARUK2007145 is a potent, selective and cell-active PI5P4Kα/γ dual inhibitor with pIC50 of 7.3/8.1, resepctively, shows no activity against PI5P4Kβ. |
| PC-21268 |
NKG2D inhibitor 4e
NKG2D inhibitor
|
NKG2D inhibitor 4e is a small-molecule protein-protein interaction inhibitor for NKG2D with IC50 of 2.2 uM, disrupts the interaction between NKG2D and multiple protein ligands through allosteric modulation of the NKG2D receptor dimer/ligand interface. |
| PC-21262 |
C105SR
Cyclophilin inhibitor
|
C105SR is small-molecule cyclophilin inhibitor with IC50 of 5 nM for inhibition of CypD PPIase activity and 9 nM for mitochondrial swelling. |
| PC-21260 |
ABR-238901
S100A9 inhibitor
|
ABR-238901 is an orally active and potent S100A9 blocker, inhibits the interaction of S100A9 with its receptors. |
