| Cat. No. |
Product Name |
Information |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-27524 |
SAIT-PDZ-5179
GIPC1 inhibitor
|
SAIT-PDZ-5179 is a small molecule inhibitor of GAIP-interacting protein C terminus 1 (GIPC1), selectively target the PDZ domain of GIPC1 with ITC KD of 943 nM. |
| PC-27518 |
Zumododstat
DHODH inhibitor
|
Zumododstat is a potent, selective inhibitor of dihydro-orotate dehydrogenase (DHODH). |
| PC-27512 |
MAT2A inhibitor ZS34
MAT2A inhibitor
|
MAT2A inhibitor ZS34 is a potent, selective, and orally bioavailable MAT2A inhibitor with IC50 of 13.7 nM. |
| PC-27506 |
JXL020
MPC inhibitor
|
JXL020 is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 16.6 nM. |
| PC-27463 |
Alpha-D-Glucose-1-phosphate disodium
CAS 56401-20-8
|
α-D-Glucose-1-phosphate disodium (Fosdemannose) is a derivative of D-glucose as a starting material for glucuronic acid synthesis, also is a cytostatic compound, antibiotic and immunosuppressant. |
| PC-27438 |
Uniconazole
ABA catabolism inhibitor
|
Uniconazole is a plant growth retardant and potent inhibitor of abscisic acid (ABA) catabolism in Arabidopsis with IC50 of 68 nM for ABA 8’-hydroxylase, also is a potent competitive inhibitor of CYP707A3 activity with Ki of 8 nM, inhibits gibberellin biosynthesis. |
| PC-27435 |
DIBDO
GSDMD agonist
|
DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells. |
| PC-27433 |
Retro-2.2
Retrograde transport inhibitor
|
Retro-2.2 is a derivative of cellular retrograde transport inhibitor Retro-2, inhibits human respiratory syncytial virus (hRSV) replication in cell culture and impairs the ability of hRSV to form syncytia. |
| PC-27432 |
Retro-2 cycl
Retrograde transport inhibitor
|
Retro-2(cycl) (Retro-2 cycl) is a small molecule inhibitor of host retrograde trafficking, inhibits ricin and Shiga-like toxins (SLTs), inhibits infection by JCPyV, BKPyV, and simian virus 40 (SV40). |
