| Cat. No. |
Product Name |
Information |
| PC-21057 |
C10M
CRP inhibitor
|
C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays. |
| PC-21028 |
PIP-199
RMI-MM2 inhibitor
|
PIP-199 is a small-molecule inhibitor of the Fanconi anemia complementation group M-RecQ-mediated genome instability protein (FANCM-RMI) protein-protein interaction, inhibits RMI core complex with Kd of 3.4 uM. |
| PC-21018 |
Mito-LND
OxPhos inhibitor
|
Mito-LND (Mito-lonidamine) is a tumor-selective inhibitor of oxidative phosphorylation with IC50 of 1.2 and 2.4 uM for mitochondrial complexes I and II, respectively, impacts the activity of mitochondrial complexes, ROS generation and peroxiredoxin oxidation. |
| PC-21007 |
NPAS3 inhibitor 6
NPAS3 inhibitor
|
NPAS3 inhibitor 6 is a highly potent neuronal PAS domain protein 3 (NPAS3) inhibitor with IC50 of 282 nM, blocks the NPAS3-ARNT heterodimerization by covalently conjugating ARNT Cys336 residue. |
| PC-21001 |
HYGIC
|
HYGIC is a small molecule that simultaneously induces hypocotyl elongation and thickening via the ethylene signaling pathway activated by endogenous ethylene. |
| PC-20988 |
Tax-1-hDLG1 inhibitor 3
Tax-1-hDLG1 inhibitor
|
Tax-1-hDLG1 inhibitor 3 is a small molecule inhibitor of Tax-1-hDLG1 interaction with EC50 of 11.5 uM, blocks HTLV-1 cell to cell transmission and viral replication. |
| PC-20964 |
DX2-201
OXPHOS complex I inhibitor
|
DX2-201 is a potent and selective oxidative phosphorylation (OXPHOS) complex I inhibitor with IC50 of 312 nM in NAD/NADH assays. |
| PC-20937 |
NV930
FTSJ1 inhibitor
|
NV930 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo. |
| PC-20936 |
NV848
FTSJ1 inhibitor
|
NV848 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo. |
| PC-20935 |
NV914
FTSJ1 inhibitor
|
NV914 is a small molecule inhibitor of tRNA-specific 2′-O-methyltransferase (FTSJ1), exerts readthrough activity in vitro and in vivo. |
| PC-20933 |
GSK898
KMO inhibitor
|
GSK898 is a potent, highly selective kynurenine monooxygenase (KMO) inhibitor with pIC50 of 8.8. |
| PC-20931 |
CIN-16645
|
CIN-16645 (LP-01) is an ionizable cationic amino lipid used in combination with other lipids in the formation of lipid nanoparticles (LNPs) to deliver single-guide RNA (sgRNA) targeting MHC class II transactivator (CIITA) in T cells. |
