| Cat. No. |
Product Name |
Information |
| PC-20868 |
Imanixil
LDLR inducer
|
Imanixil (HOE402) is a small molecule inducer of the LDL receptor (LDLR), HOE402 is a potent cholesterol-lowering compound, inhibits VLDL production. |
| PC-20866 |
ARUK200282
PI5P4Kα inhibitor
|
ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ. |
| PC-20859 |
LI-2242
IP6K inhibitor
|
LI-2242 is a potent pan-IP6K inhibitor with IC50 of with IC50 of 31, 42 and 8.1 nM for IP6K1, IP6K2 and IP6K3, respectively. |
| PC-20846 |
CC-410
NNMT inhibitor
|
CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT). |
| PC-20828 |
LAG-3 inhibitor SA-15-P
LAG-3 inhibitor
|
LAG-3 inhibitor SA-15-P is a small molecule dual inhibitor of LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 of 4.21 and 6.52 uM, respectively. |
| PC-20827 |
DFTD
eEF-2K inhibitor
|
DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K. |
| PC-20821 |
PKA inhibitor H89
PKA inhibitor
|
PKA inhibitor H89 (H-89 dihydrochloride) is a potent, selective cAMP-dependent protein kinase A (PKA) inhibitor with IC50 of 48 nM, weakly inhibits PKG, PKC, casein kinases. |
| PC-20814 |
Legumain inhibitor 7r
Legumain inhibitor
|
Legumain inhibitor 7r is a highly potent Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 0.9 nM. |
| PC-20813 |
Legumain inhibitor 10t
Legumain inhibitor
|
Legumain inhibitor 10t is a potent, selective and cellularly active Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 71 nM. |
| PC-20812 |
Legumain inhibitor 38u
Legumain inhibitor
|
Legumain inhibitor 38u is a selective inhibitor of asparagine endopeptidase (AEP, Legumain) with IC50 of 160 nM, inhibits cancer metastasis. |
| PC-20808 |
L524-0366
FN14 inhibitor
|
L524-0366 is a small-molecule inhibitor of Fn14, binds specifically to the Fn14 receptor and disrupts TWEAK-Fn14 interaction. |
| PC-20794 |
CK147
Sec61 inhibitor
|
CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro. |
