| Cat. No. |
Product Name |
Information |
| PC-20581 |
RX-105
|
RX-105 (RX105) is a small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs) with anti-inflammatory properties, binds directly to glycosaminoglycans (GAGs). |
| PC-20580 |
RX-207
|
RX-207 (RX207) is a small molecule inhibitor of protein binding to glycosaminoglycans (SMIGs), inhibits protein binding to glycosaminoglycans (GAGs), inhibits inflammatory neutrophil adhesion and activity in vitro and in vivo. |
| PC-20569 |
ERAD inhibitor CP26
Dislocation inhibitor
|
ERAD inhibitor CP26 (NSC26112) is a small molecule inhibitor of Hrd1 complex-mediated dislocation, inhibits NHK dislocation in HeLa cells with IC50 of 4.45 μM in the drGFP assays, shows broad-spectrum anti-flavivirus activity. |
| PC-20554 |
YQ456
Myoferlin inhibitor
|
YQ456 (YQ-456) is a specific small molecule inhibitor of Myoferlin (MYOF) with high binding affinity (KD=37 nM) to MYOF‐C2D domain, suppresses colorectal cancer invasion in vitro with IC50 of 110 nM. |
| PC-49816 |
SS-1-148
hOAT inhibitor
|
SS-1-148 is a potent, selective inhibitor of human ornithine δ-aminotransferase (hOAT) with Ki of 60 uM, shows excellent selectivity over other related aminotransferases (e.g., GABA-AT). |
| PC-49815 |
OV329
GABA-AT inhibitor
|
OV329 (OV 329) is a highly potent inactivator of gamma-aminobutyric acid aminotransferase (GABA-AT) with Ki of 9.69 uM. |
| PC-49807 |
Muramyl Dipeptide
|
Muramyl Dipeptide is a naturally occurring component of bacterial cell walls that has the capacity to activate macrophages, is an immunological adjuvant. |
| PC-49766 |
CNS-11
Alpha-synuclein inhibitor
|
CNS-11 is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
| PC-49756 |
NB-598 maleate
Squalene epoxidase inhibitor
|
NB-598 (NB598) is a potent competitive inhibitor of squalene epoxidase (SQLE, SE, squalene monooxygenase) with IC50 of 4.4 nM (rat SE), inhibits microsomal squalene epoxidase from dog liver and Hep G2 cells with IC50 of 2.0 and 0.75 nM, respectively. |
| PC-49755 |
MM0299 analog 13
Lanosterol synthase inhibitor
|
MM0299 analog 13 (MM 0299 derivative 13) is a potent, selective, orally bioavailable, brain-penetrant inhibitor of lanosterol synthase (LSS, competition EC50=28.7 nM) with anti-proliferative activity. |
| PC-49751 |
Cl-NIO
DDAH-1 inhibitor
|
Cl-NIO is a potent, selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) with Ki of 1.3 uM, > 500-fold selectivity against arginase and endothelial nitric oxide synthase. |
| PC-49741 |
Compound 7930079
Troponin C modulator
|
Compound 7930079 is a small molecule that increase calcium sensitivity without altering systolic calcium concentration and strengthening cardiac function, is a high affinity binder of Troponin C N-terminal domain (cNTnC) with Kd of 1.45 uM. |
