| Cat. No. |
Product Name |
Information |
| PC-21871 |
FEN1-IN-4
FEN1 inhibitor
|
FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing. |
| PC-21863 |
PCiB-1
Phosphatidylcholine synthesis inhibitor
|
PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division. |
| PC-21825 |
EC5026
sEH inhibitor
|
EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain. |
| PC-21824 |
AR9281
sEH inhibitor
|
AR9281 (AR-9281, APAU) is a potent, selective and orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 8 nM and 3 nM for human and mouse sEH enzyme, respectively. |
| PC-21809 |
Tpm1.8/9-1
Tpm1.8/9 inhibitor
|
Tpm1.8/9-1 (CID 6494468) is a specific small molecule inhibitor of Tpm1.8/9, antagonizes Tpm1.8/9's effects on EMT, Wnt signaling, and resistance to chemotherapy. |
| PC-21786 |
UT-59
Scap inhibitor
|
UT-59 is a specific inhibitor of cholesterol-sensing membrane protein Scap, binds to Scap's cholesterol-binding site, blocks SREBP activation and inhibits lipid synthesis. |
| PC-21745 |
G3BP inhibitor b
G3BP inhibitor
|
G3BP inhibitor b (G3Ib) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.15 uM, blocks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
| PC-21744 |
G3BP inhibitor a
G3BP1 inhibitor
|
FAZ-3532 (G3BP inhibitor a, G3Ia) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.54 uM, blcoks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
| PC-21741 |
GPR31 antagonist SAH2
GPR31 inhibitor
|
GPR31 antagonist SAH2 (SLU-0011371) is the first highly potent and selective small molecule GPR31 antagonist, antagonizes 12(S)-HETE-induced β-arrestin recruitment with IC50 of 1.09 uM. |
| PC-21724 |
L6H21
MD-2 inhibitor
|
L6H21 is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor with binding KD value of 33.3 uM, blocks the formation of the LPS-TLR4/MD-2 complex. |
| PC-21705 |
KVS0001
SMG1 inhibitor
|
KVS0001 is a specific and bioavailable small molecule inhibitor of SMG1 kinase, disrupts nonsense mediated decay (NMD). |
| PC-21701 |
SKOG102
OLIG2 inhibitor
|
SKOG102 is a specific, brain penetrant small molecule inhibitor of protein transcription factor OLIG2 with IC50 of 1.04 uM, impacts OLIG2 DNA binding ability, inhibits human GBM4 and GBM8 cells with IC50 of 1-2 uM. |
