| Cat. No. |
Product Name |
Information |
| PC-24310 |
NFS1 inhibitor Compound 53
NFS1 inhibitor
|
NFS1 inhibitor Compound 53 is the first potent, selective inhibitor of human cysteine desulfurase (NFS1) with IC50 of 40.5 uM and Ki of 6.4 uM. |
| PC-24307 |
BPRPT0245
PTGR2 inhibitor
|
BPRPT0245 is a specific small-molecule inhibitor of prostaglandin reductase 2 (PTGR2) with IC50 of 8.92 nM, restores 15-keto-PGE2-dependent PPARγ trans-activation in HEK293T cells expressing recombinant PTGR2 with EC50 of 49.22 nM. |
| PC-24295 |
HOSU-53
DHODH inhibitor
|
HOSU-53 (JBZ-001) is a potent and selective inhibitor of DHODH with IC50 of 0.95 nM (hDHODH), exhibits potent antileukemic activity. |
| PC-24293 |
HypoxyStat
Hypoxia inducer
|
HypoxyStat is a small molecule that increase oxygen-hemoglobin binding affinity cause tissue hypoxia, binds hemoglobin, induces systemic hypoxia in mice breathing normoxic (21% O2) air. |
| PC-24230 |
Glycyrrhizin
HMGB1 inhibitor, EV-A71 inhibitor
|
Glycyrrhizin (NSC167409, Glycyrrhizic acid) is a direct HMGB1(high mobility group box 1) inhibitor, also is a specific inhibitor of EV-A71, blocks EV-A71 replication both in vivo and in vitro. |
| PC-24222 |
I3MT-3
3MST inhibitor
|
I3MT-3 (HMPSNE, 3MST inhibitor 3) is a potent, selective, cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) with IC50 of 2.7 uM. |
| PC-24167 |
Pariceract
GCase activator
|
Pariceract (LTI-291, BIA 28-6156) is an allosteric, CNS-penetrable glucosylceramidase beta (glucocerebrosidase, GCase) activator. |
| PC-24123 |
Dencatistat
CTPS1 inhibitor
|
Dencatistat (STP938) is a potent, orally bioavailable, selective inhibitor of cytidine triphosphate synthase 1 (CTPS1) with IC50 of <100 nM, specifically blocks cell proliferation of the hematological cancers. |
| PC-24108 |
LIBX-A401
ACSL4 inhibitor
|
LIBX-A401 is a potent, selective inhibitor of Acyl-coenzyme A synthetase long-chain family member 4 (ACSL4) with IC50 of 0.38 uM, MST KD of 0.72 uM, with high selectivity over ACSL3 (IC50>50 uM), protects cells from ferroptosis. |
| PC-24061 |
(R)-dMGer
KAI2 agonist
|
(+)-dMGer ((R)-dMGer) is a potent agonist of Karrikin Insensitive 2 (KAI2), inhibits KAI2 hydrolytic activity with IC50 of 0.16 uM. |
| PC-24060 |
dMGer
KAI2 agonist
|
dMGer (DesmethylGerminone) is a potent and selective HTL/KAI2 (KAI2, Karrikin Insensitive 2) agonist, inhibits KAI2-dependent dMYLG hydrolysis with IC50 of 46 nM. |
| PC-24039 |
RUN-47
NRF1 activator
|
RUN-47 is a small-molecule activator of NRF1 with EC50 of 6.43 uM in 3xPSMA4-ARE-LUC reporter assays, specifically activates NRF1 pathway. |
