| Cat. No. |
Product Name |
Information |
| PC-26919 |
SSKP-0076
Ybx1 inhibitor
|
SSKP-0076 is a small molecule inhibitor of Y-box binding protein 1 (Ybx1), inhibits invasion and migration of LM8 osteosarcoma cells. |
| PC-26882 |
SIH-002
ZMIZ1 inhibitor
|
SIH-002 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.16 uM. |
| PC-26881 |
SIH-001
ZMIZ1 inhibitor
|
SIH-001 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.498 uM. |
| PC-26874 |
A-3190
CD38 inhibitor
|
A-3190 (A3190) is a potent, selective, brain-penetrant CD38 inhibitor with IC50 of 7.2 nM and 1.2 nM for human and mouse CD38 respectively. |
| PC-26872 |
CPN-219
NMUR2 agonist
|
CPN-219 is a potent, selective, next-generation hexapeptidic neuromedin U receptor type 2 (NMUR2) agonist with EC50 value of 2.2 nM. |
| PC-26814 |
HMGCS1 inhibitor CNP7
HMGCS1 inhibitor
|
CNP7 is a potent, selective, covalent HMG-CoA synthase 1 (HMGCS1) inhibitor, reduces HMG-CoA levels and global protein prenylation. |
| PC-26793 |
MDC134
Insulinotropic molecule
|
MDC134 is a glucose-dependent insulinotropic small molecule that enhances β-cell insulin secretion in pancreatic β-cells through Ca2+ influx and cAMP-associated amplification. |
| PC-26779 |
(Z)-Ligustilide
CAS 81944-09-4
|
(Z)-Ligustilide is an orally active natural compound from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD). |
| PC-26778 |
Ligustilide
MEOX1 inhibitor
|
Ligustilide is a potential inhibitor of mesenchyme homeobox 1 (MEOX1), exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects, exerts significant antifibrotic effects through inhibition of MEOX1 and the downstream of the Hippo signalling pathway. |
| PC-26769 |
MEDS700
DHODH inhibitor
|
MEDS700 is a potent, selective, blood-brain barrier permeable hDHODH inhibitor with IC50 of 1.5 nM. |
| PC-26744 |
TTBK1-IN-2
TTBK1 inhibitor
|
TTBK1-IN-2 (Compound 29) is a potent, brain penetrant Tau-Tubulin kinase (TTBK1) inhibitor with IC50 of 0.24 uM, reduces TDP-43 phosphorylation both in vitro and in vivo. |
| PC-26724 |
MS351
CBX7 inhibitor
|
MS351 (MS-351) is a specific small molecule antagonist of chromobox 7 (CBX7) chromodomain (CBX7ChD) with Kd of approximately 500 uM by NMR titration, disrupts H3K27me3-mediated CBX7 binding to target genes in chromatin. |
