| Cat. No. |
Product Name |
Information |
| PC-26951 |
AGPS-IN-1
AGPS inhibitor
|
AGPS-IN-1 (AGPS inhibitor 2i) is a small molecule inhibitor of alkylglyceronephosphate synthase (AGPS), decreases ether lipids, cell migration and survival, specifically impairs EMT through E-cadherine, Snail, Mmp2 modulation. |
| PC-26936 |
NCGC00685960
NNMT inhibitor
|
NCGC00685960 is a highly potent, specific Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 of <10 nM, increases H3K27 trimethylation levels in ovarian cancer cells and inhibits α-SMA expression in NNMT-expressing ovarian fibroblasts, has potent antitumor activity. |
| PC-26922 |
GPR52 agonist R-185
GPR52 agonist
|
GPR52 agonist R-185 is a potent, selective, brain permeable and orally available GPR52 agonist with EC50 of 26 nM, significantly inhibits MK-801-induced hyperlocomotor behaviors in zebrafish larvae and mice. |
| PC-26919 |
SSKP-0076
Ybx1 inhibitor
|
SSKP-0076 is a small molecule inhibitor of Y-box binding protein 1 (Ybx1), inhibits invasion and migration of LM8 osteosarcoma cells. |
| PC-26882 |
SIH-002
ZMIZ1 inhibitor
|
SIH-002 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.16 uM. |
| PC-26881 |
SIH-001
ZMIZ1 inhibitor
|
SIH-001 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.498 uM. |
| PC-26874 |
A-3190
CD38 inhibitor
|
A-3190 (A3190) is a potent, selective, brain-penetrant CD38 inhibitor with IC50 of 7.2 nM and 1.2 nM for human and mouse CD38 respectively. |
| PC-26872 |
CPN-219
NMUR2 agonist
|
CPN-219 is a potent, selective, next-generation hexapeptidic neuromedin U receptor type 2 (NMUR2) agonist with EC50 value of 2.2 nM. |
| PC-26814 |
HMGCS1 inhibitor CNP7
HMGCS1 inhibitor
|
CNP7 is a potent, selective, covalent HMG-CoA synthase 1 (HMGCS1) inhibitor, reduces HMG-CoA levels and global protein prenylation. |
| PC-26793 |
MDC134
Insulinotropic molecule
|
MDC134 is a glucose-dependent insulinotropic small molecule that enhances β-cell insulin secretion in pancreatic β-cells through Ca2+ influx and cAMP-associated amplification. |
| PC-26779 |
(Z)-Ligustilide
CAS 81944-09-4
|
(Z)-Ligustilide is an orally active natural compound from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD). |
| PC-26778 |
Ligustilide
MEOX1 inhibitor
|
Ligustilide is a potential inhibitor of mesenchyme homeobox 1 (MEOX1), exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects, exerts significant antifibrotic effects through inhibition of MEOX1 and the downstream of the Hippo signalling pathway. |
