Chemical Structure : C902
Catalog No.: PC-20847Not For Human Use, Lab Use Only.
C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM.
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C902 is a small-molecule inhibitor targeting LIN28-let-7 interaction, shows dose-dependent inhibition in an EMSA validation assay with IC50 of 5 uM.
C902 enhanced thermal stability of the cold shock domain of LIN28, and increased mature let-7 levels in JAR cells
M.Wt | 577.41 | |
Formula | C27H17BrN2O6S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Lydia Borgelt, et al. ACS Med Chem Lett. 2021 Jun 10; 12(6): 893–898.
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