| Cat. No. |
Product Name |
Information |
| PC-45670 |
BRD7552
PDX1 inducer
|
BRD7552 is a small-molecule inducer of pancreatic and duodenal homeobox 1 (PDX1) expression, induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. |
| PC-47504 |
ARA290
Erythropoietin/CD131 agonist
|
ARA290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative, specific agonist of erythropoietin/CD131 heteroreceptor, improves insulin release and glucose tolerance in type 2 diabetic GK rats. |
| PC-45840 |
Azeliragon
RAGE inhibitor
|
Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule inhibitor of RAGE, inhibits sRAGE from binding to RAGE ligands, S100b, amphoterin and carboxymethyl-lysine. |
| PC-45179 |
Deferasirox
Iron chelator
|
Deferasirox is an oral iron chelator that used to reduce chronic iron overload, also induces apoptosis in myeloid leukemia cells by targeting caspase. |
| PC-45827 |
Etomoxir
CPT-1 inhibitor
|
Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) that inhibits fatty acid β-oxidation in rat liver with IC50 of 5-20 nM. |
| PC-45142 |
Miglustat hydrochloride
Glucosylceramide synthase inhibitor
|
Miglustat hydrochloride (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase). |
| PC-45141 |
Miglustat
Glucosylceramide synthase inhibitor
|
Miglustat (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase). |
| PC-45525 |
SIBA
|
SIBA (5'-Isobutylthioadenosine) is an inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM), also inhibits the ecto-5'-nucleotidase of polymorphonuclear leucocytes. |
| PC-45288 |
Mizoribine
IMPDH inhibitor
|
Mizoribine (NSC289637, HE-69) is an immunosuppressive agent that inhibits the proliferation of lymphocytes selectively, via inhibition of IMPDH, also inhibits HCV RNA replication with IC50 of 100 uM, inhibits replication of SARS-CoV. |
| PC-42251 |
N-563
|
N-563 is an analogue of deoxyspergualin that has immunostimulating activity, promotes resistance to Candida albicans infection in mice. |
| PC-42575 |
Tyrosine kinase inhibitor
|
Tyrosine kinase inhibitor (CAS 1021950-26-4) is a tyrosine kinase inhibitor. |
| PC-45197 |
Benfotiamine
|
Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) that possesses anti-inflammatory effects, upregulates antioxidative system in activated BV-2 microglia cells. |
