| Cat. No. |
Product Name |
Information |
| PC-72547 |
SG-094
TPC2 inhibitor
|
SG-094 (SG094) is a specific cytostatic two-pore channel 2 (TPC2) inhibitor with IC50 of 8.3 uM (TPC2 activator TPC2-A1-P inhibition), shows antiproliferative effect on RIL175 cells with IC50 of 3.7 uM. |
| PC-72546 |
SBI-0802936
complex I inhibitor
|
SBI-0802936 (SBI 0802936) is an analog of SMIP004-7, inhibits NADH:ubiquinone oxidoreductase (complex I), 4-6 times more potently than SMIP004-7, acting in the same uncompetitive fashion as SMIP004-7. |
| PC-72545 |
SMIP004-7
complex I inhibitor
|
SMIP004-7 is a small molecule inhibitor of mitochondrial respiration with selective in vivo anti-cancer activity, targets drug-resistant cancer cells with stem-like features by inhibiting NADH:ubiquinone oxidoreductase (complex I). |
| PC-72542 |
Compound 2F52
Vaccine adjuvant
|
Compound 2F52 is a synthetic small-molecule vaccine adjuvant for influenza virus infection, activator of innate immunity via mitochondrial stress pathways, acts independently of known TLRs and PRRs. |
| PC-72538 |
GSK-983
DHODH inhibitor
|
GSK983 (GSK-983) is a potent small-molecule antiviral agent, and a potent, competitive inhibitor of dihydroorotate dehydrogenase (DHODH) with Ki of 403 nM. |
| PC-72537 |
AL-GDa62
SUMOylation inhibitor
|
AL-GDa62 is a specific inhibitor of TCOF1, ARPC5, and UBC9, inhibits SUMOylation at low micromolar concentrations. |
| PC-72531 |
HLM006474
E2F inhibitor
|
HLM006474 is a selective small-molecule E2F inhibitor, inhibits E2F4 DNA-binding with IC50 of 29.8 uM in A549 cells. |
| PC-72525 |
X5050
REST inhibitor
|
X5050 (X-5050) is a small molecule that inhibits REST silencing in a RE1-dependent manner, targeted REST degradation. |
| PC-72504 |
ARSA-IN-1r
ARSA inhibitor
|
ARSA-IN-1r (ARSAi) is the first reversible inhibitor of human Arylsulfatase A (ARSA) with SPR KD of 21 uM and IC50 of 13.2 uM. |
| PC-72498 |
Macrocyclic peptide D4-2
CD47-SIRPα inhibitor
|
Macrocyclic peptide D4-2 is a macrocyclic peptide consisting of 15 amino acids that binds to the ectodomain of mouse SIRPα (Kd=10 nM, IgV-B6 SIRPα) and efficiently blocks CD47-SIRPα interaction in an allosteric manner (IC50=0.18 uM). |
| PC-72487 |
RIOK2 inhibitor 10
RIOK2 inhibitor
|
RIOK2 inhibitor 10 is a specific human RIOK2 inhibitor with Kd of 160 nM. |
| PC-72486 |
RIOK2 inhibitor 9
RIOK2 inhibitor
|
RIOK2 inhibitor 9 is a specific human RIOK2 inhibitor with Kd of 520 nM. |
