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Endosidin 2

Chemical Structure : Endosidin 2

CAS No.: 1839524-44-5

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Endosidin 2 (ES-2, Endosidin2)

Catalog No.: PC-70315Not For Human Use, Lab Use Only.

Endosidin 2 (Endosidin2, ES2) is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.

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10 mg $98 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Endosidin 2 (Endosidin2, ES2) is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.

Physicochemical Properties

M.Wt 414.17
Formula C15H12FIN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-fluoro-N'-(4-hydroxy-3-iodo-5-methoxybenzylidene)benzohydrazide

References

1. Zhang C, et al. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50.

2. Drakakaki G, et al. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17850-5.

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