| Cat. No. |
Product Name |
Information |
| PC-23912 |
TN2008
SRSF1 inhibitor
|
TN2008 is an effective serine arginine-rich splicing factor 1 (SRSF1) inhibitor with IC50 of 144 uM, exhibits high affinity for recombinant SRSF1 with Kd of 5.13 uM in SPR assays. |
| PC-23857 |
VK-2019
EBNA1 inhibitor
|
VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma. |
| PC-23850 |
ALT-007
Serine palmitoyltransferase inhibitor
|
ALT-007 is a potent, selective and orally bioavailable inhibitor of serine palmitoyltransferase (SPT) with enzyme IC50 of 0.54 nM. |
| PC-23833 |
EOS301984
ENT1 inhibitor
|
EOS301984 (EOS-984) is a potent, selective equilibrative nucleoside transporter 1 (ENT1) antagonist with IC50 of 339.6 nM (human ENT1), 150-fold selectivity for ENT1 versus ENT2. |
| PC-23824 |
Paquinimod
S100A9 inhibitor
|
Paquinimod (ABR-215757) is a specific inhibitor of S100A9, inhibits S100A8/S100A9 binding to RAGE, reduces diabetes-induced thrombocytosis. |
| PC-23783 |
BL001
LRH-1 agonist
|
BL001 is a specific small molecule agonist of liver receptor homologue-1 (LRH-1) with EC50 of 0.1 uM, specifically binds to and activates LRH-1. |
| PC-23762 |
SH514
IRF4 inhibitor
|
SH514 is a specific small molecule inhibitor of interferon regulatory factor 4 (IRF4) with IC50 of 2.63 uM, inhibits proliferation of IRF4-high-expressing NCI-H929 and MM.1R MM cells with IC50 of 0.08 uM and 0.11 uM, respectively. |
| PC-23716 |
G3BP1 inhibitor 129
G3BP1/2 inhibitor
|
G3BP1 inhibitor #129 is a small molecule ligand of G3BP1/2 (Ras-GTPase-activating protein SH3 domain-binding protein 1/2), binds with G3BP1 NTF2L domain with SPR KD of 3.7 uM, prevents stress granules (SGs) formation by disrupting G3BP1/caprin1 interaction. |
| PC-23673 |
TD-198946
Runx1 modulator
|
TD-198946 is a small molecule disease-modifying osteoarthritis compound, effectively repairs cartilage by promoting chondrogenic differentiation and halt osteoarthritis (OA) progression, exerts its effect through the regulation of Runx1 expression. |
| PC-23558 |
LZX-2-73
NUPR1 inhibitor
|
LZX-2-73 is a specific and effective NUPR1 inhibitor with Kd of 2.7 uM, inhibits MIA PaCa-2 cell proliferation with IC50 of 10.9 uM. |
| PC-23557 |
AJO14
NUPR1 inhibitor
|
AJO14 is a specific and effective NUPR1 inhibitor with Kd of 4.9 uM. |
| PC-23555 |
R162
GLUD1 inhibitor
|
R162 is a potent, specific inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1) with Ki of 28.6 uM, inhibits cancer cell proliferation and tumor growth. |
