| Cat. No. |
Product Name |
Information |
| PC-21825 |
EC5026
sEH inhibitor
|
EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain. |
| PC-21800 |
LY3509754
IL-17A inhibitor
|
LY3509754 is a potent, selective and oral small molecule inhibitor of IL-17A with high binding potency(KD=2.14 nM), dose-dependently prevents human IL-17A and IL-17AF from binding human IL-17RA. |
| PC-21786 |
UT-59
Scap inhibitor
|
UT-59 is a specific inhibitor of cholesterol-sensing membrane protein Scap, binds to Scap's cholesterol-binding site, blocks SREBP activation and inhibits lipid synthesis. |
| PC-21745 |
G3BP inhibitor b
G3BP inhibitor
|
G3BP inhibitor b (G3Ib) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.15 uM, blocks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
| PC-21744 |
G3BP inhibitor a
G3BP inhibitor
|
G3BP inhibitor a (G3Ia) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.54 uM, blcoks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells. |
| PC-21741 |
GPR31 antagonist SAH2
GPR31 inhibitor
|
GPR31 antagonist SAH2 (SLU-0011371) is the first highly potent and selective small molecule GPR31 antagonist, antagonizes 12(S)-HETE-induced β-arrestin recruitment with IC50 of 1.09 uM. |
| PC-21724 |
L6H21
MD-2 inhibitor
|
L6H21 is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor with binding KD value of 33.3 uM, blocks the formation of the LPS-TLR4/MD-2 complex. |
| PC-21683 |
AJ2-30
SLC15A4 inhibitor
|
AJ2-30 is a specific small molecule SLC15A4 inhibitor with IFN-α suppression IC50 of 1.8 µM and MDP transport inhibition IC50 of 2.6 µM. |
| PC-21665 |
VY-3-249
ACSS2 inhibitor
|
VY-3-249 is a a potent Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 1.2 uM in in vitro biochemical TranScreener assays. |
| PC-21664 |
AD-8007
ACSS2 inhibitor
|
AD-8007 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 0.89 uM, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells. |
| PC-21663 |
AD-5584
ACSS2 inhibitor
|
AD-5584 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 0.86 uM, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells. |
| PC-21630 |
QP5038
QPCTL inhibitor
|
QP5038 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 3.8 nM, shows promising in vitro and in vivo anti-tumor efficacies. |
