| Cat. No. |
Product Name |
Information |
| PC-27658 |
ADAR1 inhibitor H13
ADAR1 inhibitor
|
ADAR1 inhibitor H13 is potent, orally bioavailable ADAR1 modulator, exhibits potent antiproliferative activity against various cancer cell lines and selectively reduces ADAR1-mediated editing of APOBEC3D in a dose-dependent manner. |
| PC-27639 |
KPSH02
RioK1 inhibitor
|
KPSH02 is a high affinity small molecule inhibitor of Rio Kinase 1 (RioK1) homolog from Archaeoglobus fulgidus (afRioK1) with SPR KD of 39.6 nM. |
| PC-27632 |
TTBK1 inhibitor 62
TTBK1 inhibitor
|
TTBK1 inhibitor 62 is a potent, selective, brain-penetrant ATP-competitive Tau tubulin kinase 1 (TTBK1) inhibitor with IC50 of 0.89 uM, >100-fold selective over TTBK2. |
| PC-27617 |
ABT-E79
PGK1 inhibitor
|
ABT-E79 is a highly potent and selective PGK1 inhibitor, significantly inhibits TNBC cell proliferation. |
| PC-27604 |
OMDM-1
Anandamide uptake inhibitor
|
OMDM-1 is a potent, selective inhibitor of anandamide cellular uptake (ACU) with Ki of 2.4 uM, inhibits anandamide transport. |
| PC-27596 |
Isofagomine
Glycosidase inhibitor
|
Isofagomine (Afegostat) is a broad spectrum inhibitor of glycosidases, inhibits beta-glucosidase, glucoamylase, isomaltase, and alpha-glucosidase, specifically and reversibly binds lysosomal hydrolase acid β-glucosidase (GCase) in the ER with high affinity. |
| PC-27579 |
K303MP20
GPRC5B/C inhibitor
|
K303MP20 (MP20) is a small molecule inhibitor of orphan GPCR GPRC5B and GPRC5C dimerization, inhibits GPRC5B/C-mediated modulation of EP2, IP, and AT1 signaling in vitro and in vivo. |
| PC-27512 |
MAT2A inhibitor ZS34
MAT2A inhibitor
|
MAT2A inhibitor ZS34 is a potent, selective, and orally bioavailable MAT2A inhibitor with IC50 of 13.7 nM. |
| PC-27508 |
Tazbentetol
Synaptic regenerative agent
|
Tazbentetol (SPG302) is a pegylated benzothiazole derivative and synaptic regenerative small molecule, targets the cytoskeleton and induces the formation of new glutamatergic synapses. |
| PC-27505 |
JXL069
MPC inhibitor
|
Suvomipic (JXL069) is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 42.8 nM. |
| PC-27499 |
AKBA
MAT2A inhibitor
|
AKBA is a bioactive boswellic acid found in frankincense and allosteric, specific inhibitor of methionine adenosyltransferase 2A (MAT2A) with MST Kd of 129 nM, shows anti-inflammatory and anti-cancer properties. |
| PC-27497 |
SARM1 inhibitor MY-13B
SARM1 inhibitor
|
SARM1 inhibitor MY-13B is a stereoselective, covalent SARM1 inhibitor, site-specifically engage C311 in SARM1. |
