Catalog No.: PC-23519Not For Human Use, Lab Use Only.
Necrocide 1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively.
Necrocide 1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively.
Necrocide 1 (NC1) targets TRPM4 to promote Na+ influx and necrosis.
Necrocide 1 specifically activates human TRPM4, not mouse TRPM4.
Necrocide 1 (NC1) induces necrotic cell death through sodium overload (NECSO).
