| Cat. No. |
Product Name |
Information |
| PC-73044 |
Ophiopogonin D
|
Ophiopogonin-D (OP-D) is one of steroidal saponins isolated from the root of the Chinese medicinal plant Ophiopogon japonicas, possesses anti-inflammatory and anti-oxidant properties. |
| PC-73029 |
EML417
PHF20 Tudor domain inhibitor
|
EML417 is a small molecule that selectively interactes with the Tudor domain of PHF20. |
| PC-73021 |
nTRD22
TDP-43-RNA inhibitor
|
nTRD22 is a small molecule that binds to the TDP-43 N-terminal domain (Kd=143 uM), causes allosteric modulation of the RNA binding domain (RRM) of TDP-43, resulting in decreased binding to RNA in vitro. |
| PC-73020 |
rTRD01
TDP-43-RNA inhibitor
|
rTRD01 is a specific small molecule that binds to TDP-43 RRM1 and RRM2 domains (Kd=89 uM), disrupts TDP-43 interaction with the hexanucleotide RNA repeat of the disease-linked c9orf 72 gene. |
| PC-73009 |
SPL-410
SPPL2a inhibitor
|
SPL-410 (SPL410) is a highly potent, selective, orally active inhibitor SPPL2a (Signal Peptide Peptidase Like 2a) with IC50 of 9 nM. |
| PC-73006 |
Pyrcoumin
dCTPP1 inhibitor
|
Pyrcoumin is a competitive inhibitor of dCTP pyrophosphatase 1 (dCTPP1, IC50=3.3 uM), inhibits Wnt signaling with IC50 of 8.4 uM in SuperTOPFlash reporter gene assays. |
| PC-72986 |
BI-9466
|
BI-9466 (BI 9466) is the negative control of NSD3-PWWP1 domain chemical probe BI-9321. |
| PC-72977 |
NFAT-AP-1 interaction inhibitor 10
NFAT inhibitor
|
NFAT-AP-1 interaction inhibitor 10 (NFAT inhibitor compound 10) is a small-molecule inhibitor nuclear factor of activated T cells (NFAT) with IC50 of 2 uM in FRET assays. |
| PC-72976 |
FOXM1 inhibitor RCM-1
FOXM1 inhibitor
|
FOXM1 inhibitor RCM-1 (Robert Costa Memorial drug-1, RCM-1) is a small molecule potent inhibitor of FOXM1 transcription factor. |
| PC-72968 |
SOD3 inducer BNTA
SOD3 inducer
|
SOD3 inducer BNTA (BNTA) is a small molecule with ECM modulatory properties with target of Superoxide dismutase 3 (SOD3), a strong chondrogenic inducer that increased anabolism of chondrocytes in vitro. |
| PC-72962 |
TASIN-1
EBP inhibitor
|
TASIN-1 (Truncated APC selective inhibitor-1) is a small molecule that specifically kills cells with APC truncations but spares normal and cancer cells with wild-type APC, inhibits emopamil-binding protein (EBP). |
| PC-72961 |
CW3388
EBP inhibitor
|
CW3388 (CW-3388, CW3388) is a potent, cell-active Δ8,7-sterol isomerase (EBP) inhibitor, shows near-maximal effects on oligodendrocyte formation at 110 nM. |
