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Chemical Structure : VK-28
CAS No.: 312611-92-0
Catalog No.: PC-38601Not For Human Use, Lab Use Only.
VK-28 is a novel brain permeable neuroprotective iron chelator with anti-Alzheimer's disease activities, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation with IC50 of 12.7 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $128 | In stock | |
| 5 mg | $258 | In stock | |
| 10 mg | $428 | In stock | |
| 25 mg | Get quote |
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VK-28 is a novel brain permeable neuroprotective iron chelator with anti-Alzheimer's disease activities, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation with IC50 of 12.7 uM.
| M.Wt | 287.363 | |
| Formula | C16H21N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
5-[4-(2-Hydroxyethyl)piperazine-1-ylmethyl]-quinoline-8-ol |
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1. Zhu W, et al. FASEB J. 2007 Dec;21(14):3835-44.
2. Bandyopadhyay S, et al. J Neural Transm Suppl. 2006;(71):237-47.
3. Weinreb O, et al. Neurotherapeutics. 2009 Jan;6(1):163-74.
4. Moussa B H Youdim, et al. Mech Ageing Dev. 2005 Feb;126(2):317-26.
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