ML145 | GPR35 inhibitor | Probechem Biochemicals

Chemical Structure : ML145

CAS No.: 1164500-72-4

Catalog No.: PC-38607Not For Human Use, Lab Use Only.

ML145 (CID-2286812) is a selective GPR35 antagonist with IC50 of 20.1 nM, >1000-fold selectivity over GPR55.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ML145 (CID-2286812) is a selective GPR35 antagonist with IC50 of 20.1 nM, >1000-fold selectivity over GPR55.

M.Wt	482.569
Formula	C24H22N2O5S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-hydroxy-4-[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2 enylidene]-4-oxo-2- sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino] benzoic acid

1. Alkondon M, et al. Biochem Pharmacol. 2015 Feb 15;93(4):506-18.

2. Heynen-Genel S, et al. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.