| Cat. No. |
Product Name |
Information |
| PC-63120 |
MIF-IN-3bb
MIF inhibitor
|
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
| PC-63119 |
Orita-13
MIF inhibitor
|
Orita-13 is potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 17 uM. |
| PC-63118 |
ISO-66
MIF inhibitor
|
ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
| PC-63112 |
(R)-CE3F4
EPAC1 inhibitor
|
(R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2. |
| PC-63111 |
CE3F4
EPAC1 inhibitor
|
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
| PC-63110 |
HJC0338
EPAC2 antagonist
|
HJC0338 is a potent and specific EPAC2 antagonist with IC50 of 0.4 uM for competing with 8-NBD-cAMP in binding EPAC2. |
| PC-63109 |
ESI-05
EPAC2 inhibitor
|
ESI-05 is a potent EAPC2-specific antagonist that inhibits cAMP-mediated EPAC2 GEF activity with apparent IC50 of 0.43 uM. |
| PC-63108 |
HJC0197
EPAC inhibitor
|
HJC0197 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM. |
| PC-63107 |
NSC 45576
EPAC inhibitor
|
NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM. |
| PC-63106 |
NY0173
EPAC1 inhibitor
|
NY0173 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM for EPAC1. |
| PC-63105 |
HJC0726
EPAC2 inhibitor
|
HJC0726 (HJC-0726) is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor, inhibits cAMP-mediated EPAC2 GEF activity with IC50 of 1.0 uM. |
| PC-63104 |
NY0123
EPAC inhibitor
|
NY0123 is a novel potent Exchange proteins directly activated by cAMP (EPAC) antagonist with IC50 of 0.9 and 2.4 uM for EPAC1 and EPAC2, respectively. |
