| Cat. No. |
Product Name |
Information |
| PC-62753 |
Sepin-1
|
Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM. |
| PC-62745 |
DB2115
PU.1 inhibitor
|
DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
| PC-62744 |
DB2313
PU.1 inhibitor
|
DB2313 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 29 nM. |
| PC-62713 |
S1P lyase inhibitor 28
S1P lyase inhibitor
|
S1PL-IN-28 (S1P lyase inhibitor 28) is a novel S1P lyase inhibitor with in vitro IC50 of 120 nM, cell IC50 of 230 nM. |
| PC-62693 |
SLC25A20-IN-21
SLC25A20 inhibitor
|
SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells. |
| PC-62692 |
PTGR2 inhibitor 22
PTGR2 inhibitor
|
PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells. |
| PC-62689 |
Brequinar
DHODH inhibitor
|
Brequinar (DuP785, NSC 368390) is a potent and selective inhibitor of DHODH with IC50 of 20 nM, triggers differentiation in the ER-HoxA9, U937, and THP1 cells with an ED50 of 1 uM. |
| PC-62688 |
Perhexiline maleate
CPT1/CPT2 inhibitor
|
Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
| PC-62687 |
Perhexiline
|
Perhexiline is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
| PC-62671 |
MJN228
NUCB1 ligand
|
MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1) with IC50 of 3.3 uM (blocks AEA-DA probe labeling of NUCB1). |
| PC-62658 |
Retro 2
Ricin inhibitor
|
Retro 2 (Retro-2) is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface. |
| PC-62657 |
Retro 1
Ricin inhibitor
|
Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface. |
