NXY-059 (Disufenton sodium) is a free radical-trapping agent that demonstrates a considerable neuroprotective effect in vivo.
NXY-059 exhibits a substantial protective effect, lessening the disability caused by an experimentally induced stroke in a primate species.
NXY-059 shows significantly decreased neurological impairment in rat model of hemorrhagic stroke.
Physicochemical Properties
M.Wt
381.3329
Formula
C11H13NNa2O7S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1,3-Benzenedisulfonic acid, 4-[[(1,1-dimethylethyl)oxidoimino]methyl]-, sodium salt (1:2)
References
1. Marshall JW, et al. Stroke. 2001 Jan;32(1):190-8.
