Chemical Structure : BI-1935
CAS No.: 940954-41-6
Catalog No.: PC-63248Not For Human Use, Lab Use Only.
BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $228 | In stock | |
10 mg | $368 | In stock | |
25 mg | Get quote | ||
50 mg | Get quote | ||
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM.
BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM.
BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats.
BI-1935 also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.
M.Wt | 498.466 | |
Formula | C24H21F3N6O3 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
1-(2-ethoxyethyl)-6-oxo-N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-yl)-1,6-dihydropyridine-3-carboxamide |
1. Patent WO2007067836A2.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright