You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-JBSNF-000088
JBSNF-000088

Chemical Structure : JBSNF-000088

CAS No.: 7150-23-4

JBSNF-000088 (JBSNF000088;6-Methoxynicotinamide)

Catalog No.: PC-63249Not For Human Use, Lab Use Only.

JBSNF-000088 (6-Methoxynicotinamide) is a small molecule nicotinamide analog that inhibits Nicotinamide N-methyltransferase (NNMT) with IC50 of 1.8, 2.8 and 5.0 µM for human, monkey and mouse NNMT, respectively.

Packing Price Stock Quantity
100 mg $98 In stock
200 mg $148 In stock
500 mg $228 In stock
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JBSNF-000088 (6-Methoxynicotinamide) is a small molecule nicotinamide analog that inhibits Nicotinamide N-methyltransferase (NNMT) with IC50 of 1.8, 2.8 and 5.0 µM for human, monkey and mouse NNMT, respectively.
JBSNF-000088 reduces body weight, improves insulin sensitivity and normalizes glucose tolerance in mice with high fat diet (HFD)-induced obesity.
JBSNF-000088 also improves glucose handling in ob/ob and db/db mice albeit to a lesser extent and in the absence of weight loss.

Physicochemical Properties

M.Wt 152.153
Formula C7H8N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Methoxynicotinamide

References

1. Kannt A, et al. Sci Rep. 2018 Feb 26;8(1):3660.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: