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Chemical Structure : JBSNF-000088
CAS No.: 7150-23-4
Catalog No.: PC-63249Not For Human Use, Lab Use Only.
JBSNF-000088 (6-Methoxynicotinamide) is a small molecule nicotinamide analog that inhibits Nicotinamide N-methyltransferase (NNMT) with IC50 of 1.8, 2.8 and 5.0 µM for human, monkey and mouse NNMT, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $98 | In stock | |
| 200 mg | $148 | In stock | |
| 500 mg | $228 | In stock | |
| 1 g | Get quote |
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JBSNF-000088 (6-Methoxynicotinamide) is a small molecule nicotinamide analog that inhibits Nicotinamide N-methyltransferase (NNMT) with IC50 of 1.8, 2.8 and 5.0 µM for human, monkey and mouse NNMT, respectively.
JBSNF-000088 reduces body weight, improves insulin sensitivity and normalizes glucose tolerance in mice with high fat diet (HFD)-induced obesity.
JBSNF-000088 also improves glucose handling in ob/ob and db/db mice albeit to a lesser extent and in the absence of weight loss.
| M.Wt | 152.153 | |
| Formula | C7H8N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
6-Methoxynicotinamide |
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1. Kannt A, et al. Sci Rep. 2018 Feb 26;8(1):3660.
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