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D-Fagomine

Chemical Structure : D-Fagomine

CAS No.: 53185-12-9

D-Fagomine (Fagomine)

Catalog No.: PC-43315Not For Human Use, Lab Use Only.

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.
D-Fagomine counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales, reduces the amount of Enterobacteriales excreted by rats fed HFHS.

Physicochemical Properties

M.Wt 147.1723
Formula C6H13NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: ≥ 36 mg/mL

Chemical Name/SMILES

3,4-Piperidinediol, 2-(hydroxymethyl)-, (2R,3R,4R)-

References

1. Molyneux RJ, et al. J Nat Prod. 1993 Aug;56(8):1356-64.

2. Molinar-Toribio E, et al. Food Funct. 2015 Aug;6(8):2614-9.

3. Mena-Barragán T, et al. Eur J Med Chem. 2016 Oct 4;121:880-891.

4. Ramos-Romero S, et al. Obesity (Silver Spring). 2014 Apr;22(4):976-9.

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