D-Fagomine (Fagomine)

Chemical Structure : D-Fagomine

CAS No.: 53185-12-9

Catalog No.: PC-43315Not For Human Use, Lab Use Only.

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.

Packing	Price	Stock
1 mg	$178	In stock
5 mg	$388	In stock
10 mg	$598	In stock
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Biological Activity

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.
D-Fagomine counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales, reduces the amount of Enterobacteriales excreted by rats fed HFHS.

Physicochemical Properties

M.Wt	147.1723
Formula	C6H13NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	H2O: ≥ 36 mg/mL
Chemical Name/SMILES	3,4-Piperidinediol, 2-(hydroxymethyl)-, (2R,3R,4R)-

References

1. Molyneux RJ, et al. J Nat Prod. 1993 Aug;56(8):1356-64.

2. Molinar-Toribio E, et al. Food Funct. 2015 Aug;6(8):2614-9.

3. Mena-Barragán T, et al. Eur J Med Chem. 2016 Oct 4;121:880-891.

4. Ramos-Romero S, et al. Obesity (Silver Spring). 2014 Apr;22(4):976-9.