Chemical Structure : KHK-IN-8 hydrochloride
Catalog No.: PC-43253Not For Human Use, Lab Use Only.
KHK-IN-8 is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM..
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KHK-IN-8 is a potent ketohexokinase (KHK) inhibitor with IC50 of 12 nM, interacts with Asp-27B in the ATP-binding region of KHK, also shows potent cellular KHK inhibition with IC50 of <500 nM.
M.Wt | 459.0107 | |
Formula | C21H27ClN8S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Maryanoff BE, et al. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43.
2. Maryanoff BE, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5326-9.
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