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Cat. No. Product Name Information
PC-62412

PDD 00017273

PARG inhibitor

PDD 00017273 (PDDX-001) is the first-in-class, selective inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with Kd, biochemical EC50 of 1.45 nM, 26 nM.
PC-62411

GPI 16552

PARG inhibitor

GPI 16552 is a potent, specific poly(ADP-ribose) glycohydrolase (PARG) inhibitor with IC50 of 1.7 uM.
PC-62403

CI-976

ACAT-1 inhibitor

CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM, also inhibits sterol O-acyltransferase 1 (SOAT1) with IC50 of 6.95 uM (hSOAT1).
PC-62394

AGPS inhibitor 1a

AGPS inhibitor

AGPS inhibitor 1a (AGPS-IN-1a) is a potent inhibitor of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS), selectively lowers ether lipid levels in several types of human cancer cells and impairs their cellular survival and migration.
PC-62388

ML358

SKN-1 inhibitor

ML358 is a first in class, selective small molecule inhibitor of the SKN-1 pathway with IC50 of 0.24 uM.
PC-62387

OSMI-1

O-GlcNAc transferase inhibitor

OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM.
PC-62386

P11

PAFAH inhibitor

PAFAH inhibitor P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively.
PC-62382

RH01687

RH01687 is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death.
PC-62380

TD-1

Hemoglobin modulator

Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
PC-62379

BCI-137

BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.
PC-62369

BRD56491

ROS inducer

BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer..
PC-62368

BRD9092

ROS inducer

BRD9092 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer..

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