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Chemical Structure : DDD85646
CAS No.: 1215010-55-1
Catalog No.: PC-62880Not For Human Use, Lab Use Only.
DDD 85646 is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | $758 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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DDD85646 (IMP-366) is a potent, specific, dual N-Myristoyltransferase NMT1/NMT2 inhibitor with IC50 of 17 nM/22 nM respectively.
DDD 85646 (IMP-366) inhibits myristoylation of an overexpressed protein construct in-cell-based microscopy assays.
DDD 85646 (IMP-366) has no significant affect protein synthesis in cells.
DDD 85646 (IMP-366) causes complete inhibition of N-myristoylation in cells at 1-10 uM.
DDD 85646 (IMP-366) induces ER-stress, cell cycle arrest, and apoptosis in cancer cells.
| M.Wt | 495.423 | |
| Formula | 21H24Cl2N6O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,6-dichloro-4-(2-(piperazin-1-yl)pyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide |
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