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Chemical Structure : PSB-12553
Catalog No.: PC-62917Not For Human Use, Lab Use Only.
PSB-12553 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.5 nM for rat recombinant eN.
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PSB-12553 is an α,β-Methylene-ADP (AOPCP) derivative, potent, selective ecto-5′-Nucleotidase (eN, CD73) inhibitor with Ki of 9.5 nM for rat recombinant eN.
PSB-12553 displays high selectivity versus other ecto-nucleotidases and ADP-activated P2Y receptors, has high metabolic stability.
| M.Wt | 532.401 | |
| Formula | C18H22N4O9P2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bhattarai S, et al. J Med Chem. 2015 Aug 13;58(15):6248-63.
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