| Cat. No. |
Product Name |
Information |
| PC-23929 |
CDNB
TrxR inhibitor
|
CDNB is a selective small molecule inhibitor of thioredoxin reductase (TrxR), inhibits TrxR activity with IC50 of 9.4 uM in raw macrophages. |
| PC-23928 |
MitoCDNB
TrxR2 inhibitor
|
MitoCDNB is a mitochondria-targeted molecule that disrupts thiol redox state and inhibits TrxR2, selectively disrupts mitochondrial thiol redox state in cells and in vivo, selectively depletes the mitochondrial GSH pool. |
| PC-23924 |
Nitrobenzylthioinosine
ENT1 inhibitor
|
Nitrobenzylthioinosine (NBMPR) is a specific equilibrative nucleoside transporter 1 (ENT1, SLC29A1)) inhibitor that binds to ENT1 transporter with high affinity. |
| PC-23923 |
Dilazep dihydrochloride
ENT1 inhibitor
|
Dilazep dihydrochloride is a small molecule adenosine reuptake inhibitor (AdoRI) and equilibrative nucleoside transporter 1 (ENT1) inhibitor (Ki=151.4 nM), shows cerebral and coronary vasodilating action through enhancement of effect of adenosine. |
| PC-23917 |
JH-ENT-01
ENT1 inhibitor
|
JH-ENT-01 is a potent, specific inhibitor of the equilibrative nucleoside transporter subtype 1 (ENT1) with Ki of 92.7 nM, shows good selectivity for hENT1 over hENT2. |
| PC-23907 |
Norathyriol
CAS 3542-72-1
|
Norathyriol (Mangiferitin) is a natural metabolite of Mangifera, inhibits α-glucosidase in a noncompetitive manner with IC50 of 3.12 uM, also inhibits inhibits PPARα, PPARβ, and PPARγ with IC50 of 90-100 uM, is also an effective inhibitor that targets the MEG pocket on the circPETH-147aa surface. |
| PC-23847 |
ZiMo12.8
ZIP12 inhibitor
|
ZiMo12.8 is a small molecule inhibitor of astrocytic zinc transporter ZIP12. |
| PC-23825 |
BSc5367
Nek1 inhibitor
|
BSc5367 is a potent, selective inhibitor of NIMA-related protein kinase Nek1 (NimA related kinase 1) with IC50 of 11.5 nM. |
| PC-23822 |
Butylphthalide
6066-49-5
|
Butylphthalide (3-n-Butylphthalide, NBP) is an active molecule against cerebral ischemia, shows neuroprotective activity for acute ischemic stroke. |
| PC-23814 |
Cefcapene pivoxil hydrochloride hydrate
GSDMD inhibitor
|
Cefcapene pivoxil hydrochloride hydrate (Compound 98) is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity, also is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0. 32uM), exert pyroptosis inhibitory effects. |
| PC-23813 |
SCR-1481B1
GSDMD inhibitor
|
SCR-1481B1 (Metatinib anhydrous, Compound 68) is a specific small molecule inhibitor of gasdermin D (GSDMD) targeting the GSDMD N-terminal oligomerization interface I (MST KD=0.4 uM), exert pyroptosis inhibitory effects, also shows inhibition on Met activation VEGFR. |
| PC-23808 |
ARC39
Acid sphingomyelinase inhibior
|
ARC39 is a direct, selective acid sphingomyelinase (ASM) inhibitor with IO50 of 20 nM, inhibits both lysosomal and secretory ASM in vitro. |
