| Cat. No. |
Product Name |
Information |
| PC-22160 |
KML110
NUCB1 ligand
|
KML110 is a selective ligand for the lipid-binding protein nucleobindin-1 (NUCB1) with IC50 of 9.6 uM. |
| PC-22154 |
OU749
GGT inhibitor
|
OU749 is a potent, species-specific inhibitor of human gamma-glutamyl transpeptidase (GGT) with Ki of 17.6 uM. |
| PC-22145 |
WX-02-23
FOXA1 ligand
|
WX-02-23 is a covalent small molecule ligand of transcription factor FOXA1 with EC50 of 2 uM in NanoBRET assay, binds cysteine (C258) and promotes the stereoselective and site-specific binding of FOXA1 to DNA. |
| PC-22076 |
Sulfopin
Pin1 inhibitor
|
Sulfopin is a potent, selective and covalent inhibitor of Pin1 with Ki of 17 nM in FP assay, targets Pin1's active site Cys113, blocks Myc-driven tumors. |
| PC-22060 |
Ternatin-4
eEF1A inhibitor
|
Ternatin-4 is a small molecule elongation factor-1alpha (eEF1A) inhibitor, triggers the ubiquitination and degradation of eEF1A on stalled ribosomes, targets the complex of eEF1A bound to aminoacyl-tRNAs (aa-tRNA). |
| PC-21999 |
N-chloroacetyltryptamine
AANAT inhibitor
|
N-chloroacetyltryptamine is a potent in vitro and in vivo AANAT acetyltransferase inhibitor with IC50 of 5.2 uM. |
| PC-21998 |
AANAT inhibitor 1
AANAT inhibitor
|
AANAT inhibitor 1 is a highly potent arylalkylamine N-acetyltransferase (AANAT) inhibitor with IC50 of 500 nM, covalently reacts with AANAT product CoASH. |
| PC-21975 |
Canlitinib
|
Canlitinib is a tyrosine kinase inhibitor, extracted from patent WO2018072614 (IV-2). |
| PC-21972 |
Bezisterim
|
Bezisterim (HE3286) is an orally bioavailable synthetic analogue of an active DHEA metabolite, displays both glucose-lowering and cholesterol-lowering effects. |
| PC-21959 |
Tunicamycin
N-glycosylation inhibitor
|
Tunicamycin is a homologous nucleoside antibiotic and GlcNAc phosphotransferase (GPT) inhibitor, inhibits N-glycosylation and induces ER-stress, inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity. |
| PC-21945 |
EBP inhibitor 11
EBP inhibitor
|
EBP inhibitor 11 is a potent, selective, brain-penetrant, orally bioavailable inhibitor of emopamil binding protein (EBP) with mGCMS zymo EC50 of 8 nM, and OPC differentiation EC50 of 44 nM. |
| PC-21942 |
PU.1 inhibitor A11
PU.1 inhibitor
|
PU.1 inhibitor A11 is a small molecule inhibitor of transcription factor PU.1 with EC50 of 2.5 nM in reporter assays, moderates the inflammatory response in human iPSC-derived microglia-like cells (iMGLs) by downregulating inflammatory PU.1-target gene expression without affecting hematopoiesis. |
