| Cat. No. |
Product Name |
Information |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-26826 |
Cetrimonium bromide
EBNA1 inhibitor
|
Cetrimonium bromide (CetB) is a specific small-molecule inhibitor of Epstein-Barr virus (EBV) latently infected cancer cells, reduces EBNA1 protein stability, activates G1 arrest and early apoptosis of EBV-latently infected cells without viral lytic reactivation, modulates canonical and non-canonical TGF-β signaling pathways, inhibits cancer cell migration and invasion. |
| PC-26823 |
KG-296
CLOCK/NPAS2 PAS-A inhibitor
|
KG-296 is a small molecule ligand that bind to the PAS-A domain of NPAS2 and its paralog CLOCK, binds to CLOCK PAS-A with Kd of 120 uM, specifically binds to CLOCK/NPAS2 PAS-A domains, inhibits DNA binding to CLOCK:BMAL1. |
| PC-26819 |
Myricoside
B4GALT3 inhibitor
|
Myricoside is a phenylethanoid triglycoside from Phlomis oppositiflora and small molecule β‑1,4‑galactosyltransferase III (B4GALT3) inhibitor. |
| PC-26815 |
Acarbose
alpha-glucosidase inhibitor
|
Acarbose (BAY g 5421) is an antihyperglycemic agent and orally active alpha-glucosidase (α-glucosidase) inhibitor with IC50 of 11 nM, potentiates the hypoglycemic effects of sulfonylureas or insulin. |
| PC-26814 |
HMGCS1 inhibitor CNP7
HMGCS1 inhibitor
|
CNP7 is a potent, selective, covalent HMG-CoA synthase 1 (HMGCS1) inhibitor, reduces HMG-CoA levels and global protein prenylation. |
| PC-26812 |
BI-0115
LOX-1 inhibitor
|
BI-0115 is a selective small molecule inhibitor of lectin-like oxidized LDL receptor-1 (LOX-1) with IC50 of 5.4 uM, blocks cellular uptake of oxidized low-density lipoproteins (oxLDL). |
| PC-26802 |
CNT2198
DES1 inhibitor
|
CNT2198 is a potent, selective dihydroceramide desaturase 1 (DES1) inhibitor, lowers renal ceramides, increases dihydroceramides, and shifts complex sphingolipid saturation without evidence of off-target effects. |
