| Cat. No. |
Product Name |
Information |
| PC-20790 |
GO-203
MUC1-C inhibitor
|
GO-203 (GO203) is a cell-penetrating peptide inhibitor of mucin-1-cycloplasmic C-terminal subunit (MUC1-C), blocks homodimerization of the MUC1-C subunit required for nuclear translocation and downstream signaling. |
| PC-20782 |
Piericidin A
Complex I inhibitor
|
Piericidin A is a natural insecticide isolated from the spore forming bacterium Streptomyces mobaraensis, Piericidin A is a mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. |
| PC-20780 |
DX3-234
OXPHOS inhibitor
|
DX3-234 is a potent selective complex I oxidative phosphorylation (OXPHOS) inhibitor with IC50 of 42.6 nM in NAD+/NADH assay and IC50 of 29 nM in ATP depletion assay using MIA PaCa-2 cells. |
| PC-20764 |
SW088799
Glucagon release inhibitor
|
SW088799 is a small molecule glucagon release inhibitor with IC50 of 1.26 uM, with minimal impact on insulin release. |
| PC-20754 |
BACH1 inhibitor M2
Bach1 inhibitor
|
BACH1 inhibitor M2 is a small molecule inhibitor of the transcription factor BTB and CNC homolog 1 (BACH1), inhibits AFB1-induced porcine and human cell death in vitro and AFB1-induced symptoms of weight loss and liver injury in vivo. |
| PC-20751 |
FSHR agonist 21f
FSHR agonist
|
FSHR agonist 21f is a small molecule allosteric agonist of follicle stimulating hormone receptor (FSHR) with high affinity and activation efficacy (pEC50=7.72). |
| PC-20750 |
TOP5300
FSHR agonist
|
TOP5300 (TOP05300) is a potent, selective, orally active allosteric agonist of follicle stimulating hormone receptor (FSHR) with EC50 of 9.72 nM, 80-fold selectivity over hLHR. |
| PC-20749 |
TOP5668
FSHR agonist
|
TOP5668 (TOP05668) is a potent, selective, orally active allosteric agonist of follicle stimulating hormone receptor (FSHR) with EC50 of 2.2 nM, 80-fold selectivity over hLHR. |
| PC-20736 |
F759
Cyclophilin inhibitor
|
F759 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
| PC-20735 |
F83236
Cyclophilin inhibitor
|
F83236 is a nonpeptidic small-molecule cyclophilin inhibitor, inhibits coagulation induced by procoagulant platelets. |
| PC-20718 |
BPN-14136
RBP4 inhibitor
|
BPN-14136 is a potent, selective and non-retinoid RBP4 antagonist with SPA IC50 of 12.8 nM and HTRF IC50 of 43.6 nM. |
| PC-20717 |
RBP4 antagonist 59
RBP4 inhibitor
|
RBP4 antagonist 59 is a potent, selective and orally bioavailable retinol-binding protein 4 (RBP4) antagonist with HTRF IC50 of 16 nM. |
