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Cat. No. Product Name Information
PC-21972

Bezisterim

Bezisterim (HE3286) is an orally bioavailable synthetic analogue of an active DHEA metabolite, displays both glucose-lowering and cholesterol-lowering effects.
PC-21959

Tunicamycin

N-glycosylation inhibitor

Tunicamycin is a homologous nucleoside antibiotic and GlcNAc phosphotransferase (GPT) inhibitor, inhibits N-glycosylation and induces ER-stress, inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.
PC-21945

EBP inhibitor 11

EBP inhibitor

EBP inhibitor 11 is a potent, selective, brain-penetrant, orally bioavailable inhibitor of emopamil binding protein (EBP) with mGCMS zymo EC50 of 8 nM, and OPC differentiation EC50 of 44 nM.
PC-21942

PU.1 inhibitor A11

PU.1 inhibitor

PU.1 inhibitor A11 is a small molecule inhibitor of transcription factor PU.1 with EC50 of 2.5 nM in reporter assays, moderates the inflammatory response in human iPSC-derived microglia-like cells (iMGLs) by downregulating inflammatory PU.1-target gene expression without affecting hematopoiesis.
PC-21926

AZ9567

MAT2A inhibitor

AZ9567 is a potent, selective methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 1 nM, selectively targets MTAP-deficient cancer cells.
PC-21924

MAGMAS inhibitor BT9

MAGMAS inhibitor

MAGMAS inhibitor BT9 is a small molecule MAGMAS (mitochondria associated, granulocyte-macrophage colony stimulating factor signaling molecule) inhibitor with binding Kd of 33 uM.
PC-21923

Epoxykynin

sEH inhibitor

Epoxykynin is a potent, selective  soluble epoxide hydrolase (sEH) with IC50 of 36 nM, inhibits the hydrolase activity of sEH and modulates kynurenine pathway.
PC-21895

MAT2A inhibitor 29

MAT2A inhibitor

MAT2A inhibitor 29 (AZ-29) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 27.9 nM.
PC-21877

AKST1220

LTA4H inhibitor

AKST1220 is a potent, specific leukotriene A4 hydrolase (LTA4H) inhibitor, improves hippocampal dependent memory.
PC-21871

FEN1-IN-4

FEN1 inhibitor

FEN1-IN-4 is a specific, competitive inhibitor of human flap endonuclease-1 (hFEN1) with IC50 of 30 nM, binds to atalytic metals and blocks DNA unpairing.
PC-21866

Them1 inhibitor U1

Them1 inhibitor

Them1 inhibitor U1 is a selective, allosteric small molecule inhibitor of thioesterase superfamily member 1 (Them1) with IC50 of 8.64 uM, selectively bind the Them1 START domain with Kd of 5.97 uM.
PC-21865

PCiB-3

Phosphatidylcholine synthesis inhibitor

PCiB-3 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 0.4 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2.

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