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12-deoxyphorbol 13-palmitate

Chemical Structure : 12-deoxyphorbol 13-palmitate

CAS No.: 66583-59-3

12-deoxyphorbol 13-palmitate

Catalog No.: PC-22870Not For Human Use, Lab Use Only.

12-deoxyphorbol 13-palmitate is a potent inhibitor of hepatic stellate cell (HSC) activation, directly and specifically targets apolipoprotein L2 (APOL2).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

12-deoxyphorbol 13-palmitate is a potent inhibitor of hepatic stellate cell (HSC) activation, directly and specifically targets apolipoprotein L2 (APOL2).

Physicochemical Properties

M.Wt 586.9
Formula C36H58O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

[(1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] hexadecanoate

References

1. Gan L, et al. Nat Chem Biol. 2024 Aug 5. doi: 10.1038/s41589-024-01704-3.

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