Catalog No.: PC-22886Not For Human Use, Lab Use Only.
CD80 inhibitor 1 is a specific small molecule inhibitor of human CD80 with SPR KD of 125 nM, antagonize CD28 (TR_FRET EC50=630 nM) and CTLA-4 binding to CD80, inhibits the release of the proinflammatory cytokines IL-2, IFNγ, and TNFα at submicromolar doses in T cell costimulation assays.
CD80 inhibitor 1 is a specific small molecule inhibitor of human CD80 with SPR KD of 125 nM, antagonize CD28 (TR_FRET EC50=630 nM) and CTLA-4 binding to CD80, inhibits the release of the proinflammatory cytokines IL-2, IFNγ, and TNFα at submicromolar doses in T cell costimulation assays.
