| Cat. No. |
Product Name |
Information |
| PC-45280 |
Adrenosterone
HSD11β1 inhibitor
|
Adrenosterone is a steroid hormone with a weak androgenic effect, and an intermediate/prohormone of 11-ketotestosterone, a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1). |
| PC-42312 |
Importazole
Importin β inhibitor
|
Importazole is a specific, cell permeable transport receptor Importin-β inhibitor that disrupts Ran GTP/importin-β interaction. |
| PC-45040 |
BAMB-4
ITPKA inhibitor
|
BAMB-4 is a specific and membrane-permeable inhibitor of the InsP3Kinase activity of ITPKA (inositol-1,4,5-trisphosphate-3-kinase A) with IC50 of 20 uM. |
| PC-42621 |
BIM-46187
Gαq/11 inhibitor
|
BIM-46187 (PH-064)) is a selective small molecule inhibitor of Gαq/11 proteins, directly binds to the Galpha subunit, prevents the conformational changes of the receptor-G protein complex associated with GPCR activation. |
| PC-45735 |
3PO
PFKFB3 inhibitor
|
PFKFB3 inhibitor 3PO is a small-molecule, competitive inhibitor of PFKFB3 isozyme with IC50 of 23 uM. |
| PC-45384 |
Amcasertib
Cancer stem cells inhibitor
|
Amcasertib (BBI503) is a small-molecule inhibitor that inhibits Nanog and other CSC (cancer stem cells) pathways by targeting kinases. |
| PC-45763 |
Mirin
MRE11 inhibitor
|
(Z)-Mirin is a small molecule inhibitor of MRN (Mre11-Rad50-Nbs1) pathway that inhibits Mre11-associated exonuclease activity. |
| PC-45557 |
RR6
Vanin inhibitor
|
RR6 is a selective, reversible, and competitive Vanin inhibitor with IC50 of 0.54 uM for hVVN1 pantetheinase (vanin-1). |
| PC-45331 |
Bromethalin
|
Bromethalin is a rodenticide that poisons the central nervous system by uncoupling mitochondrial oxidative phosphorylation, which causes a decrease in adenosine triphosphate (ATP) synthesis. |
| PC-42291 |
Conduritol B epoxide
β-glucosidase inhibitor
|
Conduritol B epoxide is a potent, specific, irreversible glucocerebrosidase (acid β-glucosidase) inhibitor with Ki of 53 uM. |
| PC-42264 |
Rbin-1
Midasin inhibitor
|
Rbin-1 (Ribozinoindole-1) is a potent, specific and reversible inhibitor of eukaryotic ribosome biogenesis that targets the AAA+ protein Midasin (IC40=1 uM). |
| PC-42268 |
TN1
HbF inducer
|
TN1 is a potent, small molecule fetal hemoglobin (HbF) inducer with EC50 of 100 nM. |
