Galvestine-1 | MGDG synthase inhibitor

Chemical Structure : Galvestine-1

CAS No.: 1087311-82-7

Galvestine-1 (Galvestine 1)

Catalog No.: PC-62193Not For Human Use, Lab Use Only.

Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding.

Packing	Price	Stock
1 mg	$188	In stock
5 mg	$398	In stock
10 mg	$588	In stock
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Biological Activity

Galvestine-1 is a small molecule MGDG (monogalactosyldiacylglycerol) synthase inhibitor with IC50 of 10 uM by competing with diacylglycerol binding.
Galvestine-1 shows effect of root uptake, circulation in the xylem and mesophyll, inhibition of MGDs in vivo causing a reduction of MGDG content and impairment of chloroplast development in Arabidopsis thaliana.
Galvestine-1 is a unique tool to study lipid homeostasis in plants.

Physicochemical Properties

M.Wt	498.627
Formula	C30H34N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[(2S)-2-(dibenzylamino)propyl] 4-(2-oxo-3H-benzimidazol-1-yl)piperidine-1-carboxylate

References

1. Botté CY, et al. Nat Chem Biol. 2011 Sep 25;7(11):834-42.

2. Boudière L, et al. Mol Biosyst. 2012 Aug;8(8):2023-35, 2014.

3. Botella C, et al. Plant Physiol. 2016 Mar;170(3):1300-14.

Galvestine-1 (Galvestine 1)

Biological Activity

Physicochemical Properties

References

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