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Chemical Structure : Triphenyl compound A
CAS No.: 21306-65-0
Catalog No.: PC-62245Not For Human Use, Lab Use Only.
Triphenyl compound A (TPh A) is a small-molecule inhibitor of nuclear protein Pirin with Kd of 0.6 uM, inhibits the interaction between pirin and Bcl3 in vitro and in cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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Triphenyl compound A (TPh A) is a small-molecule inhibitor of nuclear protein Pirin with Kd of 0.6 uM, inhibits the interaction between pirin and Bcl3 in vitro and in cells.
TPh A does not exerts any potent cytotoxic activity against many human cancer cell lines after 48 h of treatment, dose-dependently inhibits melanoma cell migration.
TPh A reduces SNAI2 expression by suppressing SNAI2 promoter activity, and thereby impedes melanoma cell migration.
| M.Wt | 399.523 | |
| Formula | C21H21NO3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-{[4-(Benzyloxy)phenyl](methyl)-lambda4-sulfanylidene}-4-methylbenzenesulfonamide |
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1. Miyazaki I, et al. Nat Chem Biol. 2010 Sep;6(9):667-73.
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