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WWL229

Chemical Structure : WWL229

CAS No.: 1338575-28-2

WWL229 (WWL 229, WWL-229)

Catalog No.: PC-62252Not For Human Use, Lab Use Only.

WWL229 is a selective, distinct Carboxylesterase Ces3 inhibitor with IC50 of 1.94 uM, but not Ces1f, ABHD6, other serine hydrolases.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

WWL229 is a selective, distinct Carboxylesterase Ces3 inhibitor with IC50 of 1.94 uM, but not Ces1f, ABHD6, other serine hydrolases.
WWL229 recapitulates the effects of WWL113 in adipocytes, promotes lipid storage in cultured adipocytes and prevents basal lipolysis.

Physicochemical Properties

M.Wt 322.361
Formula C16H22N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3-methoxypropyl)-1-piperidinecarboxylic acid, 4-nitrophenyl ester

References

1. Dominguez E, et al. Nat Chem Biol. 2014 Feb;10(2):113-21.

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