| Cat. No. |
Product Name |
Information |
| PC-49857 |
Acoramidis
Transthyretin stabilizer
|
Acoramidis (AG10) is a potent and selective kinetic stabilizer and ligand of transthyretin (TTR) ligand with apparent binding constant (Kapp) of 193 nM for WT-TTR. |
| PC-49851 |
Nalacin
group II GH3 inhibitor
|
Nalacin is a small molecule that partially mimicks the effects of auxin and potent inhibitor of indole-3-acetic acid (IAA) conjugation mediated by group II GH3 (Gretchen Hagen 3) in vascular plants, inhibits Gretchen Hagen 3 (GH3) acyl acid amido synthetases. |
| PC-49847 |
EP055
Sperm EPPIN inhibitor
|
EP055 (EP-055) is a small molecule that targets epididymal protease inhibitor (EPPIN) on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
| PC-49819 |
EG-011
WASP activator
|
EG-011 (WASP activator EG-011, EG011) is a first-in-class, small molecule activator of the auto-inhibited form of Wiskott-Aldrich syndrome protein (WASp) with selective anti-tumor activity in lymphomas. |
| PC-49803 |
ClpP agonist TR-65
ClpP agonist
|
ClpP agonist TR-65 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.3 nM. |
| PC-49802 |
ClpP agonist TR-57
ClpP agonist
|
ClpP agonist TR-57 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 15.5 nM. |
| PC-49801 |
ClpP agonist TR-27
ClpP agonist
|
ClpP agonist TR-27 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.7 nM. |
| PC-49788 |
DHODH inhibitor M62
DHODH inhibitor
|
DHODH inhibitor M62 is a potent, selective dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 6.9 nM. |
| PC-49783 |
JNJ-DHODH-IN-29
DHODH inhibitor
|
JNJ-DHODH-IN-29 is a potent, selective DHODH inhibitor with IC50 of 0.3 nM, inhibits MOLM-13 cell proliferation with IC50 of 0.4 nM. |
| PC-49782 |
JNJ-DHODH-IN-19
DHODH inhibitor
|
JNJ-DHODH-IN-19 is a potent, selective DHODH inhibitor with IC50 of 1.1 nM, inhibits MOLM-13 cell proliferation with IC50 of 2.0 nM. |
| PC-49779 |
JNJ-74856665
DHODH inhibitor
|
JNJ74856665 (JNJ74856665) is an orally available, potent and selective DHODH inhibitor with IC50 of 0.4 nM. |
| PC-49767 |
CNS-11g
Alpha-synuclein inhibitor
|
CNS-11g is a small molecules capable of disassembling preformed alpha-synuclein fibrils, may exert it's disaggregating effects on the N terminus of the fibril core. |
