| Cat. No. |
Product Name |
Information |
| PC-42367 |
Thyroxine sulfate
|
Thyroxine sulfate (T4 Sulfate) is a major Thyroid hormone metabolite secreted by follicular cells of the Thyroid gland, T4 is involved in controlling the rate of metabolic processes in the body and influencing physical development, a prohormone and a reservoir for the active thyroid hormone triiodothyronine (T3). |
| PC-63179 |
TRIF agonist AV-C
TRIF agonist
|
TRIF agonist AV-C is a novel TRIF pathway agonist that activates innate and interferon-associated responses, strongly inhibits replication of ZIKV, CHIKV, and DENV (IC90~5 uM). |
| PC-63145 |
Verdiperstat
MPO inhibitor
|
Verdiperstat (AZD3241) is a potent, selective, reversible, orally active myeloperoxidase (MPO) inhibitor with IC50 of 630 nM, >14-fold selectivity over thyroid peroxidase (TPO). |
| PC-63120 |
MIF-IN-3bb
MIF inhibitor
|
MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM. |
| PC-63119 |
Orita-13
MIF inhibitor
|
Orita-13 is potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 17 uM. |
| PC-63118 |
ISO-66
MIF inhibitor
|
ISO-66 is a novel, highly stable, small-molecule MIF inhibitor that inhibits MIF tautomerase activity with IC50 of 1.4 uM. |
| PC-63112 |
(R)-CE3F4
EPAC1 inhibitor
|
(R)-CE3F4 is a more potent, selective EPAC1 antagonist than the racemic CE3F4 and (S)-CE3F4, displays 10-fold selectivity for EPAC1 over EPAC2. |
| PC-63111 |
CE3F4
EPAC1 inhibitor
|
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity. |
| PC-63110 |
HJC0338
EPAC2 antagonist
|
HJC0338 is a potent and specific EPAC2 antagonist with IC50 of 0.4 uM for competing with 8-NBD-cAMP in binding EPAC2. |
| PC-63109 |
ESI-05
EPAC2 inhibitor
|
ESI-05 is a potent EAPC2-specific antagonist that inhibits cAMP-mediated EPAC2 GEF activity with apparent IC50 of 0.43 uM. |
| PC-63108 |
HJC0197
EPAC inhibitor
|
HJC0197 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM. |
| PC-63107 |
NSC 45576
EPAC inhibitor
|
NSC 45576 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 1.7 uM. |
