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Chemical Structure : PH002
CAS No.: 1311174-68-1
Catalog No.: PC-63439Not For Human Use, Lab Use Only.
PH002 is a small-molecule structure corrector significantly decreased ApoE4 fragment levels in ApoE4/4-hiPSC-derived neurons, increases GABAergic neuron numbers and GAD67 levels, reduces p-tau levels, and decreases Aβ40 and Aβ42 production and/or secretion.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $358 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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PH002 is a small-molecule structure corrector significantly decreased ApoE4 fragment levels in ApoE4/4-hiPSC-derived neurons, increases GABAergic neuron numbers and GAD67 levels, reduces p-tau levels, and decreases Aβ40 and Aβ42 production and/or secretion.
| M.Wt | 491.58 | |
| Formula | C27H33N5O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-[[4-[[2-(3,4-Dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester |
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1. Wang C, et al. Nat Med. 2018 Apr 9. doi: 10.1038/s41591-018-0004-z.
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