Catalog No.: PC-63355Not For Human Use, Lab Use Only.
Compound-326 (D5D inhibitor 326, D5D-IN-326) is apotent, selective, orally active delta-5 desaturase (D5D, FADS1/Fatty Acid Desaturase 1) with IC50 of 72 and 22 nM for rat and human D5D, respectively.
Compound-326 (D5D inhibitor 326, D5D-IN-326) is apotent, selective, orally active delta-5 desaturase (D5D, FADS1/Fatty Acid Desaturase 1) with IC50 of 72 and 22 nM for rat and human D5D, respectively.
Compound-326 shows no inhibition for both rat and human D6D and D9D activity.
Compound-326 lowers insulin resistance and caused body weight loss without significant impact on cumulative calorie intake in high-fat diet-induced obese (DIO) mouse model.
