Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-LBL1
LBL1

Chemical Structure : LBL1

CAS No.: 1605301-58-3

Add to Favorites

LBL1 (Lamin A inhibitor LBL1)

Catalog No.: PC-63448Not For Human Use, Lab Use Only.

LBL1 (Lamin A inhibitor LBL1) is a novel pyrroloquinazoline compound with significant anticancer activity, targets nuclear lamins and binds to the coiled-coil domain of lamin A (Kd=5.11 uM).

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    LBL1 (Lamin A inhibitor LBL1) is a novel pyrroloquinazoline compound with significant anticancer activity, targets nuclear lamins and binds to the coiled-coil domain of lamin A (Kd=5.11 uM).
    LBL1 demonstrates growth inhibitory activities against MDA-MB-468 and MDA-MB-231 breast cancer cell lines with GI50 of 0.44 and 1.60 uM, respectively.
    LBL1 binds to LA(1-387) both in vitro and in living cells.

    Physicochemical Properties

    M.Wt 353.385
    Formula C21H15N5O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(1-amino-7H-pyrrolo[3,2-f]quinazolin-3-yl)-2-naphthamide

    References

    1. Chen J, et al. Medchemcomm. 2013 Sep 1;4(9):1275-1282.

    2. Li BX, et al. ACS Chem Biol. 2018 Apr 19. doi: 10.1021/acschembio.8b00266.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: