| Cat. No. |
Product Name |
Information |
| PC-38501 |
MrgX1 modulator 8e
MrgX1 modulator
|
MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, showed improved potency and microsomal stability than ML382. |
| PC-38482 |
CYM2503
GalR2 PAM
|
CYM2503 is a putative galanin receptors type 2 (GalR2) positive allosteric modulator, concentration-dependently potentiates galanin (100 nM) stimulated IP1 accumulation in HEK293-GalR2 cells with EC50 of 0.69 uM, efficacy of 9.7-fold potentiation. |
| PC-38445 |
ML180
LRH1 (NR5A2) inhibitor
|
ML180 (SR-1848) is a potent, selective Liver Receptor Homologue-1 (LRH1, NR5A2) inverse agonist with IC50 of 3.7 uM in reporter assays, displays no activity against SF1 (NR5A1). |
| PC-38444 |
ML179
LRH1 (NR5A2) inhibitor
|
ML179 (SR-1309, PubChem CID 45100448) is a potent, selective Liver Receptor Homologue-1 (LRH1, NR5A2) inverse agonist with IC50 of 320 nM in reporter assays, displays no activity against SF1 (NR5A1). |
| PC-38443 |
A-286982
LFA-1/ICAM-1 inhibitor
|
A-286982 is a potent, nonpeptide inhibitor of LFA-1/ICAM-1 interaction with IC50 of 44 and 35 nM in LFA-1/ICAM-1 binding assay and LFA-1-mediated cellular adhesion assay, respectively. |
| PC-38436 |
NEK7 inhibitor M12
NEK7 inhibitor
|
NEK7 inhibitor M12 is a novel potent inhibitor of NEK7 protein. |
| PC-38433 |
Zenuzolac
Immunosuppressant
|
Zenuzolac (GLS1027, VGX-1027) is a small molecule immunosuppressant and an orally available isoxazole compound, inhibits toll-like receptor 4 (TLR4) activity, has shown promise for the treatment of several neuroinflammatory disorders. |
| PC-38413 |
FHT-1204
BRM/BRG1 inhibitor
|
FHT-1204 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50 of < 10 nM. |
| PC-38412 |
Phevamine A
Virulence factor
|
Phevamine A is a widely distributed virulence factor in phytopathogens, Phevamine A promotes bacterial growth by suppressing plant immune responses. |
| PC-38411 |
BRD8518
TRIB1 inducer
|
BRD8518 is a specific small molecule TRIB1 inducer, modulates expression of the key genes involved in VLDL production and in LDL clearance in HepG2 cells. |
| PC-38410 |
BRD0418
TRIB1 inducer
|
BRD0418 is a specific small molecule that upregulate TRIB1 expression and phenocopy the effects of TRIB1 cDNA overexpression (EC50=1 uM, TRIB1 overexpression in HepG2 cells). |
| PC-38407 |
RJW100
LRH-1 (NR5A2) agonist
|
RJW100 (RJW 100) is a phospholipid mimetic as liver receptor homolog-1 (LRH-1, NR5A2) agonist with pEC50 of 6.6 and 7.5 for (LRH-1) and steroidogenic factor-1 (SF-1, NR5A1), respectively. |
