| Cat. No. |
Product Name |
Information |
| PC-61243 |
r(GGGGCC)n binder 1a
|
A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM. |
| PC-61242 |
UNC-3230
PIP5K1C inhibitor
|
UNC-3230 (UNC3230) is a selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks. |
| PC-61241 |
SPRi3
|
SPRi3 (SPR inhibitor 3) is a small molecule inhibitor of sepiapterin reductase (SPR) with IC50 of 74 nM in cell-free assays, efficiently reduces biopterin levels with IC50 of 5.2 uM. |
| PC-61236 |
AGI-1067
|
AGI-1067 (Succinobucol) is a potent inhibitor of TNF-α-inducible expression of VCAM-1, MCP-1 and E-selectin (IC50=6,10 and 25 uM) with concurrent antioxidant and lipid-modulating properties. |
| PC-61225 |
DFPM
Abscisic acid inhibitor
|
DFPM is a small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure. |
| PC-61214 |
Pyrimidinone 8
DMT1 inhibitor
|
Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM. |
| PC-61208 |
Ferristatin II
Iron transport inhibitor
|
Ferristatin II (NSC 8679, NSC8679, Chlorazol Black) is a small molecule iron transport inhibitor that promotes degradation of transferrin receptor-1 in vitro and in vivo, through a nystatin-sensitive lipid raft pathway. |
| PC-61207 |
NSC 306711
Iron transport inhibitor
|
NSC 306711 (Ferristatin, NSC306711) is a small-molecule iron transport inhibitor that promotes degradation of the transferrin receptor independent of clathrin and dynamin, is sensitive to the cholesterol-depleting agents filipin and nystatin. |
| PC-70268 |
Shz-1
Nkx2.5 inducer
|
Shz-1 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells. |
| PC-70267 |
Shz-3
Nkx2.5 inducer
|
Shz-3 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells. |
| PC-70265 |
RNase L-IN-2
|
RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM. |
| PC-70260 |
Compound A5
AP-1 inhibitor
|
Compound 5431942 (Compound 5431942) is a small molecule that specifically inhibits the clathrin adaptor complex AP-1-dependent traffic, does not significantly affect other pathways through the trans-Golgi network (TGN). |
