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Sodium cromoglicate

Chemical Structure : Sodium cromoglicate

CAS No.: 15826-37-6

Sodium cromoglicate (Cromolyn sodium, PA-101, FPL-670, Disodium cromoglicate )

Catalog No.: PC-61794Not For Human Use, Lab Use Only.

Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.

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Biological Activity

Sodium cromoglicate (Cromolyn sodium) is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.
Sodium cromoglicate (Cromolyn sodium) also inhibits chloride channels, and binds S100P to block the interaction between S100P and RAGE.

Physicochemical Properties

M.Wt 512.334
Formula C23H14Na2O11
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylic acid)

References

1. Heinke S, et al. Br J Pharmacol. 1995 Aug;115(8):1393-8.

2. Zur E, et al. Int J Pharm Compd. 2012 Sep-Oct;16(5):386-93.

3. Penumutchu SR, et al. Biochem Biophys Res Commun. 2014 Nov 21;454(3):404-9.

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