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Cromoglicic acid

Chemical Structure : Cromoglicic acid

CAS No.: 16110-51-3

Cromoglicic acid (Cromolyn, FPL-670)

Catalog No.: PC-61795Not For Human Use, Lab Use Only.

Cromoglicic acid (Cromolyn, FPL-670) is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cromoglicic acid (Cromolyn, FPL-670) is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells.
Cromoglicic acid also inhibits chloride channels, and binds S100P to block the interaction between S100P and RAGE.

Physicochemical Properties

M.Wt 468.367
Formula C23H16O11
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid

References

1. Heinke S, et al. Br J Pharmacol. 1995 Aug;115(8):1393-8.

2. Zur E, et al. Int J Pharm Compd. 2012 Sep-Oct;16(5):386-93.

3. Penumutchu SR, et al. Biochem Biophys Res Commun. 2014 Nov 21;454(3):404-9.

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